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The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

The document concludes that non-binary individuals need compassionate support and recognition in healthcare, without being pathologized.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Platelet-rich plasma shows promise for skin and hair treatments but needs more research and standardization.

The research found that PCOS has common genetic factors regardless of how it is diagnosed and is linked to metabolic and reproductive issues.

The ginseng market has potential for growth and needs new products and better marketing.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

WNT10A mutations often cause ectodermal dysplasias, with males showing more tooth issues than females.

Targeted cancer therapies often cause serious skin problems that need careful management.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair loss affects self-esteem and quality of life; treatments can help.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.