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    Glossary Heat Shock Proteins

    help cells survive stress by stabilizing and refolding damaged proteins

    Heat Shock Proteins (HSPs) are a group of proteins that are produced by cells in response to stressful conditions, such as elevated temperatures, toxins, or other environmental stressors. They function as molecular chaperones, helping to stabilize and refold damaged proteins, thereby protecting cells from stress-induced damage. HSPs are crucial for maintaining cellular function and integrity, and their role is significant in various biological processes, including protein homeostasis and the stress response.

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    1. Molecular functional analyses revealed essential roles of HSP90 and lamin A/C in growth, migration, and self-aggregation of dermal papilla cells Cell death discovery · 2018 · 10 citations
    2. Importance of dietary supplementation of soluble and insoluble fibers to sows subjected to high ambient temperatures during late gestation and effects on lactation performance Animal nutrition · 2024
    3. Calreticulin: non‐endoplasmic reticulum functions in physiology and disease The FASEB Journal · 2009 · 341 citations
    4. Investigation of In Vitro and In Silico Anti-Inflammatory Potential of Carthamus caeruleus L. Root Juice International Journal of Molecular Sciences · 2025 · 2 citations
    5. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations
    6. Microneedles meet photomedicine: emerging strategies for diagnosis and therapy of skin diseases Nanoscale Advances · 2026
    7. Chapter 6 Fetal Skin Wound Healing Advances in Clinical Chemistry · 2009 · 89 citations
    8. A Comprehensive Review on Current and Future Trends of Nanoemulsions in Modern Cosmetics and Pharmaceuticals International Journal of Advanced Science and Engineering · 2025 · 2 citations
    9. Androgenetic Alopecia Springer eBooks · 1996 · 8 citations
    10. Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos 2023
    11. Melatonin Promotes the Development of Secondary Hair Follicles in Adult Cashmere Goats by Activating the Keap1-Nrf2 Signaling Pathway and Inhibiting the Inflammatory Transcription Factors NFκB and AP-1 International Journal of Molecular Sciences · 2023 · 1 citations
    12. Extracellular Vesicles in Skin Wound Healing Pharmaceuticals · 2021 · 106 citations
    13. Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring Stem Cell Research & Therapy · 2021 · 45 citations
    14. Tissue Regeneration, Stem Cells, and Wound Healing Journal of Investigative Dermatology · 2012 · 3 citations
    15. Efficacy and Safety of Ablative Fractional CO <sub>2</sub> Laser Therapy for Localized Scleroderma: A Comprehensive Bench‐to‐Bedside Approach Dermatologic Therapy · 2025
    16. Research Progress on the Immunomodulatory Effects by Dang Gui (Radix Angelica sinensis) and Its Active Chemical Components Molecules · 2026
    17. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    18. Mycobacterial 65,000 MW heat-shock protein shares a carboxy-terminal epitope with human epidermal cytokeratin 1/2. PubMed · 1992 · 31 citations
    19. Expression of the heat shock protein-27 in the adult human scalp skin and hair follicle: Hair cycle–dependent changes Journal of the American Academy of Dermatology · 2006 · 24 citations
    20. Heat shock protein 25 plays multiple roles during mouse skin development Cell Stress and Chaperones · 2005 · 14 citations
    21. The Role of Heat Shock Proteins in the Pathogenesis of Polycystic Ovarian Syndrome: A Review of the Literature International Journal of Molecular Sciences · 2023 · 3 citations
    22. Elevated serum heat shock protein-70 and interleukin-15: prognostic biomarkers correlating with clinical severity and diagnostic efficacy in active alopecia areata Journal of the Egyptian Womenʼs Dermatologic Society · 2026
    23. Correlation of immunological variables of interleukin-17 and heat shock protein-70 in ethnic women with polycystic ovary syndrome South Eastern European Journal of Public Health · 2024
    24. Correlation of Immunological Variables of Interleukin-17 and Heat Shock Protein-70 In Ethnic Women with Polycystic Ovary Syndrome South Eastern European Journal of Public Health · 2024
    25. Up-regulation of androgen receptor by heat shock protein 27 and miR-1 induces pathogenesis of androgenic alopecia. PubMed · 2022
    26. Single-cell analysis of basal cell carcinoma reveals heat shock proteins promote tumor growth in response to WNT5A-mediated inflammatory signals bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 1 citations
    27. Risks of Protein Conditioner Application under the Impact of Heat and/or Gamma Irradiation in Albino Rats 2021
    28. Dietary supplementation with L-glutamine enhances immunity and reduces heat stress in Hanwoo steers under heat stress conditions 2022 · 3 citations
    29. Vitamin A regulates dermal papilla cell proliferation and apoptosis under heat stress via IGF1 and Wnt10b signaling Ecotoxicology and environmental safety · 2023 · 2 citations
    30. Structural Characterization and Ligand Specific Protein Interactions of Androgen Receptor The Knowledge Bank (The Ohio State University) · 2008