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    Did you mean Hair Placodes?
    Glossary Hair Placodes

    small skin thickenings initiating hair follicle development

    Hair placodes are small, thickened areas of skin that form during early embryonic development and serve as the initial sites for hair follicle formation. These structures are crucial because they signal the underlying dermal cells to start the complex process of hair follicle development, eventually leading to hair growth.

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    1. The Rho GTPase regulator ARHGEF3 orchestrates hair placode budding by coordinating cell fate and P-cadherin patterning in mice PLoS Biology · 2026
    2. miR-29a-5p Inhibits Prenatal Hair Placode Formation Through Targeting EDAR by ceRNA Regulatory Network Frontiers in Cell and Developmental Biology · 2022
    3. The combination of hair follicle-specific marker LHX2 and co-expressed marker can distinguish between sweat gland placodes and hair placodes in rat Journal of Molecular Histology · 2021 · 5 citations
    4. LHX2 is a direct NF-κB target gene that promotes primary hair follicle placode down-growth Development · 2016 · 43 citations
    5. Radially patterned morphogenesis of murine hair follicle placodes ensures robust epithelial budding Developmental Cell · 2024 · 8 citations
    6. Molecular principles of hair follicle induction and morphogenesis BioEssays · 2005 · 479 citations
    7. Identification of dkk4 as a target of Eda-A1/Edar pathway reveals an unexpected role of ectodysplasin as inhibitor of Wnt signalling in ectodermal placodes Developmental biology · 2008 · 117 citations
    8. Sostdc1 defines the size and number of skin appendage placodes Developmental biology · 2012 · 56 citations
    9. Transcriptomic landscape of early hair follicle and epidermal development Cell Reports · 2023 · 23 citations
    10. Fate Before Function: Specification of the Hair Follicle Niche Occurs Prior to its Formation and Is Progenitor Dependent bioRxiv (Cold Spring Harbor Laboratory) · 2018 · 2 citations
    11. Author response: Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation 2018 · 1 citations
    12. Research Highlights: γδ T cells regulate hair follicle neogenesis during adult wound healing Regenerative Medicine · 2013
    13. Transcriptomic landscape of early hair follicle and epidermal development bioRxiv (Cold Spring Harbor Laboratory) · 2022
    14. 872 Dermal Wnt/β-catenin signaling controls hair follicle dermal condensate size during development Journal of Investigative Dermatology · 2017
    15. EDA and EDAR expression at different stages of hair follicle development in cashmere goats and effects on expression of related genes 2020 · 12 citations
    16. 1387 Identifying the key niche signals for hair follicle formation Journal of Investigative Dermatology · 2018
    17. KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin Development · 2009 · 82 citations
    18. ARHGEF3 Regulates Hair Follicle Morphogenesis 2024
    19. Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis Development · 2004 · 293 citations
    20. Prenatal hair development: Implications for drug exposure determination Forensic science international · 2010 · 45 citations
    21. CD10 and CD34 in fetal and adult human hair follicles: dynamic changes in their immunohistochemical expression during embryogenesis and hair cycling British Journal of Dermatology · 2008 · 25 citations
    22. Sox13 is a novel early marker for hair follicle development Biochemical and Biophysical Research Communications · 2019 · 6 citations
    23. Mesenchyme governs hair follicle induction bioRxiv (Cold Spring Harbor Laboratory) · 2023
    24. 602 Sox13 is a novel marker for hair follicle development and differentiation Journal of Investigative Dermatology · 2019
    25. Morphogenetic Events in Hair Follicle Heterotypic Spheroids 2017
    26. Identification of Ectodysplasin Target Genes Reveals the Involvement of Chemokines in Hair Development 2012 · 48 citations
    27. Expression of <i>Foxi3</i> is regulated by ectodysplasin in skin appendage placodes Developmental dynamics · 2013 · 43 citations
    28. Identification of a secreted BMP antagonist, ectodin, integrating BMP, FGF, and SHH signals from the tooth enamel knot Developmental biology · 2003 · 243 citations
    29. Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis Cell death and differentiation · 2011 · 76 citations
    30. The mechanical forces that shape our senses Development · 2022 · 12 citations