research Neuroendocrinology of the Hair Follicle: Principles and Clinical Perspectives
Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
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research Rethinking Biotin Therapy for Hair, Nail, and Skin Disorders
Biotin supplements are not proven to improve hair or nails and may interfere with medical tests.
research Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway
Quercitrin may help treat hair loss by promoting hair growth and improving cell health.
research Leptin Controls Hair Follicle Cycling
Leptin helps start the growth phase of hair.
research Mechanism of Action of Androgen in Hair Follicles
Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
research Overexpression of Hypoxia-Inducible Factor-1α in Hidradenitis Suppurativa: The Link Between Deviated Immunity and Metabolism
Increased HIF-1α is linked to the inflammation and severity of hidradenitis suppurativa, suggesting treatments that lower HIF-1α could help.
research Hair Zinc and Chromium Levels Associated with Reduced Likelihood of Age-Related Cognitive Decline in Centenarians and Oldest-Old Adults
Higher hair levels of zinc and chromium were linked to less cognitive decline in very old people.
research In This Issue
Alexander the Great's engineers built a causeway using a natural sand bridge, some tiger moths avoid bats by mimicking toxic relatives' sounds, early metabolism and RNA enzymes support the ancient RNA world theory, and vitamin D is crucial for hair growth and its absence can cause baldness.
research Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells
Muscles and nerves that cause goosebumps also help control hair growth.
research Analysis of Dermal Papilla Cell Interactome Using STRING Database to Profile the Ex Vivo Hair Growth Inhibition Effect of a Vinca Alkaloid Drug, Colchicine
Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.
research Prostanoids and Hair Follicles: Implications for Therapy of Hair Disorders
Prostanoids, like prostaglandins and thromboxane A2, can both enhance and inhibit hair growth, and understanding their effects could help treat hair disorders.
research KF19418, A New Compound for Hair Growth Promotion in Vitro and in Vivo Mouse Models
KF19418 promotes hair growth similarly to minoxidil but is not better in live mice.
research An Update of Hair Shaft Disorders
Advances in genetics may lead to targeted treatments for hair disorders.
research Hydra And The Hair Follicle – An Unconventional Comparative Biology Approach To Exploring The Human Holobiont
Hydra can help understand human hair follicle microbiomes and develop new skin disease therapies.
research The Human Hair Follicle as Sentinel for Drug Evaluation: Demonstration of Tetracycline Adhesion to Hair Follicle as Proposed Mechanism in Dysfunctional Hair Loss
Tetracycline can stick to hair follicles and potentially cause hair loss.
research Finasteride 1 mg Has No Inhibitory Effect on Omeprazole Metabolism in Extensive and Poor Metabolizers for CYP2C19 in Japanese
Finasteride doesn't affect omeprazole metabolism in Japanese people.
research Role of Sulfur Metabolism Gene and High-Sulfur Gene Expression in Wool Growth Regulation in the Cashmere Goat
Certain genes related to sulfur metabolism are more active during the growth phase of Cashmere goat wool, and melatonin might help this process.
research Autophagy Induces Hair Follicle Stem Cell Activation and Hair Follicle Regeneration by Regulating Glycolysis
Autophagy helps activate hair stem cells and hair growth by changing their energy use to glycolysis.
research Defining Metabolic Flexibility in Hair Follicle Stem Cell Induced Squamous Cell Carcinoma
Blocking both main energy pathways can stop hair follicle stem cell-induced skin cancer growth.
research Role of the ABCA4 Gene Expression in the Clearance of Toxic Vitamin A Derivatives in Human Hair Follicle Stem Cells and Keratinocytes
The ABCA4 gene protects hair follicle stem cells from toxic vitamin A byproducts.
research The Effects of GPR40 Agonists on Hair Growth Are Mediated by ANGPTL4
GPR40 agonists help hair growth through the protein ANGPTL4.
research The Bacterial Metabolite, Butyrate, Prolongs Anagen and Promotes Autophagy, Mitochondrial Activity, Melanogenesis and Antimicrobial Peptide Production in Human Scalp Hair Follicles
Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
research Characterization of Xenobiotic Metabolizing Enzymes of a Reconstructed Human Epidermal Model from Adult Hair Follicles
The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.
research Morphogenetic Events in Hair Follicle Heterotypic Spheroids
The research concluded that hyaluronic acid affects the formation and growth of hair follicle-like structures in a lab setting.
research The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition During Root Hair Tip Growth
ERULUS controls root hair growth by regulating cell wall composition and pectin activity.
research Impact of Testosterone on Hair and Skin
Testosterone can cause acne and male-pattern baldness, affects hair growth in men and women, and makes male skin more sensitive.
research The Impact of Oxidative Stress on Hair
Oxidative stress damages hair and contributes to aging, and managing it can help maintain hair health.
research The Role of Correction of Metabolic Disorders in the Treatment of Androgenetic Alopecia in Women
Using a combined treatment of minoxidil and metformin can improve hair loss in women by normalizing hormone and metabolism levels.
research Cannabinoids for Skin Diseases and Hair Regrowth
Cannabinoids might help with skin diseases and hair growth, but more research is needed.
research Albendazole Treatment of Echinococcosis in Humans: Effects on Microsomal Metabolism and Drug Tolerance
Albendazole treatment for echinococcosis can cause serious side effects and requires close monitoring.