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    Glossary Hair Growth-Related Proteins

    are proteins that regulate and promote hair growth

    Hair Growth-Related Proteins are specific proteins that play crucial roles in the regulation and promotion of hair growth. These proteins include keratin, which forms the structural foundation of hair, and growth factors like fibroblast growth factor (FGF) and insulin-like growth factor (IGF), which stimulate hair follicle development and cycling. Understanding these proteins is essential for developing treatments for hair loss conditions such as alopecia.

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    1. Dickkopf-related Protein 2 Promotes Hair Growth by Upregulating the Wnt/β-catenin Signaling Pathway in Human Dermal Papilla Cells Annals of Dermatology · 2024 · 6 citations
    2. Scientific Opinion on the substantiation of health claims related to soy isoflavones and protection of DNA, proteins and lipids from oxidative damage (ID 1286, 4245), maintenance of normal blood LDL cholesterol concentrations (ID 1135, 1704a, 3093a), reduction of vasomotor symptoms associated with menopause (ID 1654, 1704b, 2140, 3093b, 3154, 3590), maintenance of normal skin tonicity (ID 1704a), contribution to normal hair growth (ID 1704a, 4254), “cardiovascular health” (ID 3587), treatment … EFSA journal · 2011 · 22 citations
    3. Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles PeerJ · 2019 · 7 citations
    4. Hair-Cycle-Dependent Expression of Parathyroid Hormone-Related Protein and its Type I Receptor: Evidence for Regulation at the Anagen to Catagen Transition 2003 · 52 citations
    5. Peer Review #2 of "Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles (v0.1)" 2019
    6. Hair growth-promoting effect of recombinant human sonic hedgehog proteins Biomedical dermatology · 2019 · 3 citations
    7. Immunolocalization of proteins related to retinoic acid synthesis and signaling during hair cycle 2009
    8. The Expression of P-Responsive Genes is Related to Root Hair Growth The Proceedings of the International Plant Nutrition Colloquium XVI · 2009 · 1 citations
    9. Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles (PGA-4HGF) by β-Catenin Activation and Its Related Cell Cycle Molecules International Journal of Molecular Sciences · 2019 · 7 citations
    10. Red ginseng oil promotes hair growth and protects skin against UVC radiation Journal of Ginseng Research · 2021 · 10 citations
    11. Effects of Ganoderma Lucidum Extract Ethanol Extract and Microneedle Therapy System on Hair Growth in an Alopecia Model of C57BL/6N Mice 2014 · 4 citations
    12. Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway Journal of microbiology and biotechnology · 2023
    13. Parathyroid Hormone Hormone-Related Protein and the PTH Receptor Regulate Angiogenesis of the Skin Journal of Investigative Dermatology · 2006 · 33 citations
    14. Millet seed oil activates β–catenin signaling and promotes hair growth Frontiers in Pharmacology · 2023 · 1 citations
    15. Establishment of 3D Spheroid Human Dermal Papilla Cells as an Effective Model for Hair Growth Screening Compounds Compared with the 2D System: An Example of Minoxidil and 3,4,5-Tri-O-caffeoylquinic acid (TCQA) Research Square (Research Square) · 2021
    16. Hair Growth Promoting Effects of Limosilactobacillus reuteri Isolated from Honeybee through Wnt/β-catenin Signal Transduction Journal of the Korean Society of Cosmetology · 2026
    17. Visible-to-Near IR Quantum Dot–Based Hypermulticolor High-Content Screening of Herbal Medicines for the Efficacy Monitoring of Hair Growth Promotion and Hair Loss Inhibition SLAS discovery · 2012 · 14 citations
    18. Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model International Journal of Molecular Sciences · 2024
    19. Partial Proteasome Inhibitors Induce Hair Follicle Growth by Stabilizing β-Catenin Stem cells · 2013 · 3 citations
    20. Hair growth–promoting effects of Enz_MoriL on human dermal papilla cells through modulation of the Wnt/β-Catenin and JAK-STAT signaling pathways Archives of dermatological research · 2024
    21. The G-Protein Couple Receptor Kinase 2 (GRK2) Orchestrates Hair Follicle Homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    22. Expression of an Olfactomedin-Related Gene in Rat Hair Follicular Papilla Cells 2005 · 10 citations
    23. Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep BMC Biology · 2021 · 112 citations
    24. Author response: A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning 2017 · 3 citations
    25. A comparative proteomic-based study identifies essential factors involved in hair follicle growth in inner Mongolia cashmere goats BMC Veterinary Research · 2025
    26. The TOR–Auxin Connection Upstream of Root Hair Growth Plants · 2021 · 20 citations
    27. The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles Open Life Sciences · 2023
    28. 1332 Janus kinase inhibitor increases hair growth by increasing beta-catenin activity in outer root sheath cells 2023
    29. 447 Skin-Associated Cartilage Consists of Lipid-Filled Cells That Modify Hair Growth via BMP and WNT Signaling Journal of Investigative Dermatology · 2025
    30. Cell surface receptor kinase FERONIA linked to nutrient sensor TORC signaling controls root hair growth at low temperature linked to low nitrate in<i>Arabidopsis thaliana</i> bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 2 citations