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    Glossary hair follicle niche

    specialized skin microenvironment regulating hair growth and regeneration

    The hair follicle niche is a specialized microenvironment within the skin where hair follicles reside. It contains various cells, signaling molecules, and extracellular matrix components that work together to regulate hair growth, cycling, and regeneration. This niche plays a crucial role in maintaining the health and function of hair follicles, and disruptions in this environment can lead to conditions like alopecia.

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    1. Review of Human Hair Follicle Biology: Dynamics of Niches and Stem Cell Regulation for Possible Therapeutic Hair Stimulation for Plastic Surgeons Aesthetic Plastic Surgery · 2018 · 22 citations
    2. Hair Follicle Stem Cells Provide a Functional Niche for Melanocyte Stem Cells Cell stem cell · 2011 · 283 citations
    3. Stem cell dynamics in the hair follicle niche Seminars in Cell & Developmental Biology · 2013 · 135 citations
    4. The Modulatable Stem Cell Niche: Tissue Interactions during Hair and Feather Follicle Regeneration Journal of Molecular Biology · 2015 · 66 citations
    5. Aging in hair follicle stem cells and niche microenvironment The Journal of Dermatology · 2017 · 38 citations
    6. The Mesenchymal Niche of the Hair Follicle Induces Regeneration by Releasing Primed Progenitors from Inhibitory Effects of Quiescent Stem Cells Cell Reports · 2018 · 35 citations
    7. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    8. Exploring Mechanical Niches Identified by Hair Follicle Compression and How These Transduce Proliferation and Differentiation Cues in Epidermally Derived cells. Durham e-Theses (Durham University) · 2019
    9. 1374 Cell-cell interaction in the hair follicle niche in androgenetic alopecia Journal of Investigative Dermatology · 2023
    10. Brief Report: Requirement of TACE/ADAM17 for Hair Follicle Bulge Niche Establishment Stem Cells · 2012 · 14 citations
    11. Hdac1 and Hdac2 regulate the quiescent state and survival of hair-follicle mesenchymal niche Nature communications · 2023 · 1 citations
    12. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    13. Faculty Opinions recommendation of Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2020
    14. Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration <i>in vivo</i> The EMBO Journal · 2019 · 44 citations
    15. Hoxc-Dependent Mesenchymal Niche Heterogeneity Drives Regional Hair Follicle Regeneration Cell Stem Cell · 2018 · 43 citations
    16. 440 Charting the Spatially Resolved Hair Follicle Stem Cell Niche: A Multi-Omics Atlas of Healthy and Diseased Scalp Journal of Investigative Dermatology · 2025
    17. Immune niches for hair follicle development and homeostasis Frontiers in physiology · 2024
    18. 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation 2016
    19. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    20. Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle bioRxiv (Cold Spring Harbor Laboratory) · 2022
    21. Transcriptional Governance of Hair Follicle Stem Cell Quiescence and Niche Maintenance in Long-Term Tissue Regeneration Digital Commons - RU (Rockefeller University) · 2025
    22. Cellular dynamics in the niche of infrequently dividing hair follicle stem cells in the mouse Mus musculus eCommons (Cornell University) · 2010
    23. The homing of exogenous hair follicle mesenchymal stem cells into hair follicle niches JCI Insight · 2023 · 6 citations
    24. Niche formed by bone morphogenetic protein antagonists gremlin 1 and gremlin 2 in human hair follicles Health Science Reports · 2022 · 5 citations
    25. Fully functional hair follicle regeneration through the rearrangement of stem cells and their niches Nature Communications · 2012 · 179 citations
    26. Aging of hair follicle stem cells and their niches Journal of Biochemistry and Molecular Biology · 2022 · 2 citations
    27. 030 Impaired Glutathione Synthesis in Hair Follicle Stem Cell Niches in Alopecia Areata Journal of Investigative Dermatology · 2025
    28. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011 · 396 citations
    29. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020 · 77 citations
    30. Regulatory T cells in skin mediate immune privilege of the hair follicle stem cell niche Science Immunology · 2024 · 21 citations