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    Glossary Growth Factors

    naturally occurring proteins that regulate cell growth and repair

    Growth factors are naturally occurring proteins or hormones that play a crucial role in regulating cell growth, proliferation, and differentiation. They are essential for various biological processes, including wound healing, tissue repair, and hair growth. In the context of hair, growth factors can stimulate hair follicles, promoting the growth of new hair and potentially aiding in the treatment of conditions like alopecia.

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    1. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth-Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019 · 136 citations
    2. Evaluation of Not-Activated and Activated PRP in Hair Loss Treatment: Role of Growth Factor and Cytokine Concentrations Obtained by Different Collection Systems International Journal of Molecular Sciences · 2017 · 136 citations
    3. Hair growth stimulated by conditioned medium of adipose-derived stem cells is enhanced by hypoxia: evidence of increased growth factor secretion Biomedical research · 2010 · 134 citations
    4. Growth factors and cytokines in hair follicle development and cycling: recent insights from animal models and the potentials for clinical therapy Molecular Medicine Today · 1996 · 100 citations
    5. Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata Archives of Dermatological Research · 1996 · 91 citations
    6. GROWTH FACTORS IN HAIR ORGAN DEVELOPMENT AND THE HAIR GROWTH CYCLE Dermatologic Clinics · 1996 · 90 citations
    7. Recent Advances in the Controlled Release of Growth Factors and Cytokines for Improving Cutaneous Wound Healing Frontiers in Cell and Developmental Biology · 2020 · 88 citations
    8. Cosmeceuticals: peptides, proteins, and growth factors Journal of Cosmetic Dermatology · 2016 · 67 citations
    9. Specific receptor detection by a functional keratinocyte growth factor-immunoglobulin chimera. 1995 · 66 citations
    10. In vivo promoted growth of mice hair follicles by the controlled release of growth factors Biomaterials · 2003 · 60 citations
    11. Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors International Journal of Molecular Medicine · 2013 · 56 citations
    12. Growth factors specifically alter hair follicle cell proliferation and collagenolytic activity alone or in combination Differentiation · 1990 · 56 citations
    13. Androgen-Dependent Beard Dermal Papilla Cells Secrete Autocrine Growth Factor(s) in Response to Testosterone Unlike Scalp Cells 1998 · 51 citations
    14. Minoxidil Promotes Hair Growth through Stimulation of Growth Factor Release from Adipose-Derived Stem Cells International Journal of Molecular Sciences · 2018 · 42 citations
    15. The effects of autologus platelet rich plasma and various growth factors on non-transplanted miniaturized hair Hair transplant forum international · 2009 · 37 citations
    16. Effects of topical application of growth factors followed by microneedle therapy in women with female pattern hair loss: A pilot study Journal of Dermatology · 2012 · 34 citations
    17. Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles International Journal of Molecular Medicine · 2011 · 28 citations
    18. The Growth Factors in Advanced Platelet-Rich Fibrin (A-PRF) Reduce Postoperative Complications after Mandibular Third Molar Odontectomy International Journal of Environmental Research and Public Health · 2021 · 23 citations
    19. Narrow-band red LED light promotes mouse hair growth through paracrine growth factors from dermal papilla Journal of Dermatological Science · 2011 · 23 citations
    20. Human umbilical cord blood mesenchymal stem cells engineered to overexpress growth factors accelerate outcomes in hair growth The Korean Journal of Physiology and Pharmacology · 2018 · 21 citations
    21. Tsukushi is involved in the wound healing by regulating the expression of cytokines and growth factors Journal of Cell Communication and Signaling · 2014 · 21 citations
    22. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    23. Adipose Derived Stem Cells and Growth Factors Applied on Hair Transplantation. Follow-Up of Clinical Outcome Journal of Cosmetics, Dermatological Sciences and Applications · 2014 · 20 citations
    24. Increment of growth factors in mouse skin treated with non-thermal plasma International journal of medical sciences · 2018 · 18 citations
    25. Growth factor concentrations in platelet‐rich plasma for androgenetic alopecia: An intra‐subject, randomized, blinded, placebo‐controlled, pilot study Experimental Dermatology · 2020 · 13 citations
    26. Development of growth factor-incorporating liposomes for integration into scaffolds as a method to improve tissue regeneration The International Journal of Developmental Biology · 2021 · 12 citations
    27. Growth Factors, Cell-Cell and Cell-Matrix Interactions in Skin during Follicle Development and Growth 1988 · 11 citations
    28. Epidermal growth factor and fibroblast growth factor accelerate proliferation of human hair bulb papilla cells and root sheath tibroblasts cultured in vitro British Journal of Dermatology · 1987 · 9 citations
    29. Growth factors IGF-1 and KGF and adipose-derived stem cells promote migration and viability of primary human keratinocytes in an in vitro wound model Frontiers in Medicine · 2025 · 8 citations
    30. Heterogeneity in amount of growth factors secreted by platelets in platelet‐rich plasma samples from alopecia patients Experimental dermatology · 2020 · 8 citations