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    Did you mean Growth Differentiation Factor 8?
    Glossary Growth Differentiation Factor 8

    inhibits muscle growth by signaling muscles to stop growing

    Growth Differentiation Factor 8 (GDF-8), also known as Myostatin, is a protein that inhibits muscle growth. It plays a crucial role in regulating muscle mass by signaling muscles to stop growing, ensuring that muscle growth does not become excessive. This protein is of particular interest in medical research for its potential implications in treating muscle-wasting diseases and enhancing muscle growth in livestock.

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    Research 30 of 1000+

    1. Fibroblast Growth Factor-9 Enhances M2 Macrophage Differentiation and Attenuates Adverse Cardiac Remodeling in the Infarcted Diabetic Heart PLOS ONE · 2015 · 44 citations
    2. Interplay between fibroblast growth factor 9 (FGF9) and CD44 underlies 46,XY disorders of sex development in Kruppel‐like factor 1 (KLF‐1)‐E325K‐associated congenital dyserythropoietic anaemia (CDA‐IV) British Journal of Haematology · 2026
    3. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis Developmental dynamics · 1998 · 252 citations
    4. Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart Oxidative Medicine and Cellular Longevity · 2015 · 17 citations
    5. Astragalus membranaceus and Cinnamomum cassia Stimulate the Hair Follicle Differentiation-Related Growth Factor by the Wnt/β-Catenin Signaling Pathway Current Issues in Molecular Biology · 2023
    6. Exploiting molecular genetic diagnoses of polycystic ovary syndrome to achieve better patient outcome Murdoch Research Repository (Murdoch University) · 2018
    7. Maintenance of high proliferation and multipotent potential of human hair follicle-derived mesenchymal stem cells by growth factors International Journal of Molecular Medicine · 2013 · 56 citations
    8. Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors Molecular Medicine Reports · 2013 · 24 citations
    9. Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. PubMed · 1997 · 107 citations
    10. Concentrated Conditioned Medium-Loaded Silk Nanofiber Hydrogels with Sustained Release of Bioactive Factors To Improve Skin Regeneration ACS Applied Bio Materials · 2019 · 5 citations
    11. Acneiform eruptions caused by an epidermal growth factor receptor-tyrosine kinase inhibitor ZD 1839 Journal of the American Academy of Dermatology · 2004 · 1 citations
    12. The Cutaneous Epidermal Growth Factor Network: Can it be Translated Clinically to Stimulate Hair Growth? Dermatology Online Journal · 2009 · 39 citations
    13. Fibroblast growth factor and epidermal growth factor in hair development 1993 · 39 citations
    14. Enhancing hair growth in male androgenetic alopecia by a combination of fractional CO2 laser therapy and hair growth factors Lasers in Medical Science · 2017 · 26 citations
    15. Fibroblasts: Immunomodulatory factors in refractory diabetic wound healing Frontiers in Immunology · 2022 · 20 citations
    16. All Roads Go to the Nucleus: Integration of Signaling/Transcription Factor-Mediated and Epigenetic Regulatory Mechanisms in the Control of Skin Development and Regeneration Stem cell biology and regenerative medicine · 2018
    17. Making the head: Caspases in life and death Frontiers in Cell and Developmental Biology · 2023 · 7 citations
    18. Genes Expression Profiling for Hair Growth by Finasteride and Luteolin Administration in Murine Model 2013
    19. Scalp Sebaceous Physiology Springer eBooks · 2017
    20. Using platelet-rich plasma to treat hair loss and thinning Journal of Aesthetic Nursing · 2020
    21. Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep BMC Biology · 2021 · 112 citations
    22. Activation of the OVOL1-OVOL2 axis in the hair bulb and in pilomatricoma and pilomatrix carcinoma Journal of dermatological science · 2016
    23. 4-Aminopyridine Induces Nerve Growth Factor to Improve Skin Wound Healing and Tissue Regeneration Biomedicines · 2022
    24. Cell Viability and Hair Growth Effect on 3T3-L1 Cells of Ethanol Extract from Calendula officinalis L. Flower, Phellinus linteus Fruit Body and Houttuynia cordata Thunb. Whole Plant Korean Journal of Medicinal Crop Science · 2017 · 2 citations
    25. Hair Follicle Keratins CRC Press eBooks · 2020 · 1 citations
    26. Hair shape of curly hair Journal of the American Academy of Dermatology · 2003 · 78 citations
    27. Acne Harper's Textbook of Pediatric Dermatology · 2011 · 2 citations
    28. Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury bioRxiv (Cold Spring Harbor Laboratory) · 2023 · 2 citations
    29. Editors' Picks Journal of Investigative Dermatology · 2017
    30. An estrogen receptor pathwayregulates thetelogen-anagen hair follicle transition andinfluences epidermal cell proliferation (epidermis/estrogen/keratinocyte/differentiation/mesenchymal 1996