36 citations
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June 2001 in “Neuroscience Letters” This study found that finasteride increased fetal arousal activity in late gestation sheep by suppressing pregnane steroid synthesis, suggesting reduced GABAA receptor-mediated inhibition.
32 citations
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September 2010 in “Stress” This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.
November 2025 in “International Journal of Women’s Dermatology” This study found that pregnancy-associated skin disorders like pemphigoid gestationis are linked to increased risks of hypertensive disorders, gestational diabetes, and preterm complications, but atopic and pustular conditions show no such risks.
August 2015 in “Arquivo Brasileiro de Medicina Veterinária e Zootecnia/Arquivo brasileiro de medicina veterinária e zootecnia” This study found that maternal caffeine intake during gestation and lactation can lead to skin lesions like hypotrichosis and alopecia in both mother and offspring rats, irrespective of maternal cortisol levels.
January 2011 in “Industrial health and Occupational Diseases” In this study, resveratrol exposure during gestation did not show significant adverse effects on the development of F1 male rats.
10 citations
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May 1986 in “Experientia” This animal study found that second generation mice exposed to excess zinc during gestation and lactation had reduced plasma copper, body weight, and hematocrit, with lighter and delayed hair development compared to mice on a normal zinc diet.
May 2016 in “Research opinions in animal & veterinary sciences” In this study, aspartame consumption during gestation in rats was associated with significant histological changes and increased apoptosis in the skin of their neonatal pups.
109 citations
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December 2003 in “American Journal of Pathology” This study observed that the ontogenetic transition from scarless repair in early fetal rat wounds to scar-forming repair in late gestation is associated with differential TGF-β ligand and receptor expression patterns.
15 citations
,
December 2021 in “Nature Communications” In studying wild meerkats, researchers observed that matriarchs with high androgen levels during late gestation exhibited increased dominance and aggression, affecting both their behavior and their offspring's aggression.
9 citations
,
October 1994 in “Brain Research” In this study, researchers observed that dorsal horn cells in fetal sheep begin responding to natural cutaneous stimulation by mid-gestation, coinciding with the initial innervation of the skin.
7 citations
,
January 2018 in “Reproduction” This study found that dutasteride treatment in pregnant mares significantly increased progesterone concentrations but did not alter gestational length or neonatal outcomes.
December 2025 in “The Journal of Basic and Applied Zoology” This study found that the prenatal skin development in Red Sokoto goats undergoes significant morphological changes across gestational stages, which may be important for their adaptation and thermoregulation after birth.
May 2025 in “Nutrition and Diabetes” This study found that elevated 1-hour plasma glucose in women with PCOS was associated with increased risk of metabolic disorders and gestational diabetes, indicating it may be a useful marker for adverse metabolic status.
June 2023 in “Lithuanian University of Health Sciences” This review found that the pathophysiology of polycystic ovary syndrome is associated with increased rates of gestational diabetes, pregnancy-induced hypertension, caesarian deliveries, and adverse effects on preterm birth and neonatal weight during pregnancy.
May 2008 in “10th European Congress of Endocrinology” This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.
This study explored the carbohydrate composition of plasma cell membranes in human embryonic epidermis over various gestational ages and found specific patterns that may inform future diagnostic and therapeutic approaches for dermatoses.
10 citations
,
April 2008 in “Journal of Pediatric Surgery” In this study, researchers found that the absence of P-selectin delays inflammatory cell recruitment and reepithelialization in fetal wounds, although scar formation still occurs in later gestation wounds.
10 citations
,
January 2001 in “PubMed” In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.
8 citations
,
August 2016 in “Journal of pathology and translational medicine” This study found that CD99 is strongly expressed in the basal cells and hair follicles of normal adult and developing fetal skin, with expression patterns becoming similar after 20 weeks of gestation.
4 citations
,
January 2019 in “Therapeutic Advances in Endocrinology and Metabolism” This review found no evidence that medications used to manage PCOS add to cardiovascular risk or prevent diabetes onset, although metformin may help prevent gestational diabetes in these patients.
3 citations
,
April 2014 in “Anatomy Research International” This study detailed the developmental stages of the buffalo mammary gland during prenatal growth, identifying key morphological features at various gestation lengths.
December 2023 in “International journal of research in dermatology” In this study, physiological skin changes like linea nigra (84.4%) and striae distensae (78.4%) were most common in pregnant women, while pathological changes were shown to be significantly associated with gravida and gestational age.
In this study, the researchers found that EGF and EGFR play crucial roles in goat fetal skin development, with their expression increasing progressively during gestation.
January 2009 in “대한피부과학회지” This study found that telogen effluvium after childbirth is more prevalent in women with higher parity, cesarean sections, greater weight gain, and later gestational age.
January 2006 in “Zhonghua miniao waike zazhi” This study established a stable rabbit model of hypospadias using finasteride, finding varied rates of the condition's severity and associated testicular retention across different gestation day treatments.
August 2019 in “Placenta” This article reviews the use of spironolactone in dermatology for conditions like female acne, suggesting it may reduce antibiotic and isotretinoin use, and stresses its long-term safety.
37 citations
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January 2005 in “Clinics in dermatology” This review discusses recent advances in understanding the genetics of hair and nail disorders and reports no new clinical results.
1 citations
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February 2017 in “International journal of anatomy and research” This study found that the progression of fetal skin development, marked by key features like the appearance of hair follicles and eccrine sweat glands, can help determine fetal age and predict congenital skin diseases.
Higher pre-pregnancy BMI is linked to more stress in mothers and more behavioral problems in two-year-old children.
May 2024 in “Journal of trace elements in medicine and biology” In this study, researchers observed that pregnant women who were overweight or obese before pregnancy had lower iron concentrations in serum and hair, as well as lower dietary iron intake, during their first trimester compared to women with normal body weight.