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Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.

As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.

Afro-textured hair needs personalized care due to its unique genetic traits.

Obesity is linked to more severe hair loss in adult men and to excess hair growth, but its effects on hair conditions are complex and need more research.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Researchers found a new gene area linked to male-pattern baldness, which, along with another gene, significantly increases the risk of hair loss in men.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

The document concludes that adult mammalian skin contains multiple stem cell populations with specific markers, important for understanding skin regeneration and related conditions.

New methods have greatly improved our understanding of stem cell behavior and roles in the body.

Nearly half of the French individuals surveyed reported having a sensitive scalp, more common in women, often linked to hair loss and symptoms like itching, and triggered by factors including shampoos and pollution.

Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.

European guidelines recommend regular eye and ear exams, skin care, vitamin D supplements, and cautious use of medications for managing congenital ichthyoses.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

Kennedy's disease leads to muscle weakness and sensory issues, has no cure but manageable symptoms, and future treatments look promising.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

Cancer development is like natural selection, involving mutated cells and environmental factors.

The document suggests treating individuals with nonclassic congenital adrenal hyperplasia who show symptoms, especially those related to excess male hormones.

Genetic differences between young and old Tan sheep explain why their fleece changes from curly to straight as they age.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Effective management of children's hair loss involves accurate diagnosis, various treatments, and supportive care.

DNA variants can predict male pattern baldness, with higher risk scores increasing baldness likelihood.

There's no significant link between the D19S884 marker at the insulin receptor gene and polycystic ovary syndrome.

The research suggests that the global distribution of PCOS is likely due to historical human migration and that genes affecting PCOS may have different impacts on males and females.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.