April 2012 in “Lab Animal” Early exposure to germs may protect against autoimmune diseases, lack of sex increases alcohol preference in fruit flies, a potential baldness treatment could involve blocking a specific receptor, skin memory cells help prevent re-infection, high-fat diets can affect brain cells related to weight, and the link between social status, stress, and heart disease in primates is unclear.
256 citations
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October 2013 in “Nature Communications” This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.
December 2024 in “Indian Dermatology Online Journal” This study presents a compilation of dermatological disorders that are descriptively compared to the "Navaratnas," or nine planetary gems from Vedic astrology, highlighting unique diagnostic terms and their clinical presentations to make dermatology more accessible and memorable for practitioners and patients.
September 2023 in “International Journal of Cosmetic Science” The researchers observed that two non-antimicrobial shampoos caused a significant increase in fungal germs but did not affect the overall scalp microbiota diversity over two weeks, suggesting these formulations may preserve or stimulate the scalp microbiota without adverse effects.
10 citations
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January 2001 in “PubMed” In this study, researchers found that the expression of laminin, collagen type IV, and fibronectin in fetal human skin begins in hair follicle germs and extends to epidermal cells by 21 weeks gestational age.
2 citations
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December 2013 in “Current Oral Health Reports” This review discusses current developments in tooth regenerative therapy, including bioengineered tooth replacements, and emphasizes its potential to fully restore tooth function, but it presents no new clinical results.
165 citations
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October 2013 in “Nature Communications” This study demonstrates that bioengineered salivary gland transplants can fully regenerate gland function, producing saliva and restoring normal swallowing in salivary gland-defective mice, offering potential for xerostomia treatment.
252 citations
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March 1998 in “Developmental dynamics” This study suggests that fibroblast growth factors FGF-4, FGF-8, and FGF-9 may play redundant roles as signals in epithelial-mesenchymal interactions during multiple stages of tooth development in mice.
May 2004 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study identified interactions between Vitamin D and Msx1 regulation pathways, noting that Msx1 overexpression decreases Vitamin D receptor expression in odontoblastic cells.
208 citations
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November 2000 in “Development” This study found that while Eda and Edar proteins interact in vitro, their roles in dental development differ, with downless mutant mice showing distinct tooth defects compared to tabby mutants.
4 citations
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January 2013 in “Inflammation and Regeneration” This review examines recent developments in tooth regeneration therapies using mesenchymal stem cells, but it reports no new clinical findings.
4 citations
,
May 2009 in “Wound Repair and Regeneration” This study found that transplanting genetically modified dermal fibroblasts into full-thickness skin defects in rats led to the formation of hair follicles with mature pilosebaceous systems by 16 weeks.
2 citations
,
March 2021 in “Journal of Pakistan Association of Dermatologists” This study found that a lack of knowledge about alopecia areata, compounded by low literacy, can lead to improper treatment and increased stress among affected individuals.
February 2024 in “Journal of Dermatological Science” This study examined the formation of acquired curved hair and found that the fusion of hair matrix cells during follicle regeneration contributes to asymmetric follicle shapes and curved hair, potentially linked to changes in type IV collagen and protein expression levels.
April 2017 in “Journal of Investigative Dermatology” This study suggests that dermal Wnt/β-catenin activation timing is crucial for hair follicle initiation, with potential non-cell autonomous regulation of dermal condensate size.
867 citations
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November 2020 in “Nature Communications” This review discusses the challenges of interpreting observational studies on COVID-19 due to biases from non-representative samples, such as collider bias, and suggests better sampling methods to mitigate these issues.
This article reviews challenges in interpreting observational COVID-19 data due to biases from non-random sampling, discussing strategies to address these biases but reporting no new results.
153 citations
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March 2017 in “Endocrine” This review examines recent advances in understanding the pathophysiology and molecular mechanisms of androgenetic alopecia, highlighting two major genetic risk loci, but does not report new clinical findings.
55 citations
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July 2016 in “Dermatologic Therapy” This article reviews treatment options for androgenetic alopecia and suggests that therapy should be personalized and targeted at various pathophysiological aspects, but reports no new clinical findings.
48 citations
,
February 2017 in “Journal of Cosmetic Dermatology” This proposal reviews current knowledge and suggests actions for managing chemotherapy‐induced alopecia but reports no new clinical results, highlighting the need for evidence‐based guidelines.
48 citations
,
January 2003 in “Fertility and Sterility” In this study, researchers found no significant association between the D19S884 marker near the insulin receptor gene and polycystic ovary syndrome in women from Spain and Italy.
37 citations
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December 2019 in “Giornale italiano di dermatologia e venereologia” This Italian guideline discusses the diagnosis and treatment of alopecia areata but reports no new clinical trial results; the authors highlight the need for well-designed studies.
37 citations
,
January 2019 in “Dermatologic Therapy” This article is a letter to the editor discussing the treatment of telogen effluvium using a dietary supplement, but it provides no new research results.
35 citations
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March 2010 in “BMC veterinary research” The study found that while a clinical protocol showed high specificity in detecting scrapie in goats, its low sensitivity suggests many cases might be missed if diagnosis is only based on clinical signs.
32 citations
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March 2021 in “Journal of cosmetic dermatology (Print)” This letter to the editor discusses a potential link between new onset alopecia areata and SARS-CoV-2 infection, but reports no new clinical results.
28 citations
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January 2021 in “Skin appendage disorders” This study observed that telogen effluvium, or acute hair loss, often occurs 1 to 3 months after SARS-CoV-2 infection, earlier than classic telogen effluvium.
25 citations
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June 2020 in “Dermatology practical & conceptual” This study reviewed treatments for chemotherapy-induced hair loss, finding that scalp cooling is FDA-approved for prevention, while minoxidil and bimatoprost may aid post-chemotherapy regrowth. The authors emphasized tailored therapies and the potential utility of tools like trichoscopy and trichogram.
23 citations
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July 2018 in “Journal of Cosmetic Dermatology” This study describes a distinct pattern of trichoscopic features associated with chemotherapy-induced alopecia and how these features evolve through different phases of chemotherapy treatment.
18 citations
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June 2017 in “Journal of The American Academy of Dermatology” In this study, trichoscopy consistently identified typical findings of frontal fibrosing alopecia, revealing three unusual clinical patterns in 18.4% of patients, which may aid in the differential diagnosis when clinical presentations are atypical.
14 citations
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January 2020 in “Women's health reports” This study found that iron therapy improved nonhematological symptoms and cognitive function in women with iron deficiency anemia, highlighting the need for attention to these symptoms in improving quality of life.