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    Glossary Gasdermin family

    group of proteins that trigger cell death and inflammation

    The Gasdermin family is a group of proteins involved in the process of cell death and inflammation. These proteins can form pores in cell membranes, leading to a type of cell death called pyroptosis, which is important for fighting infections but can also contribute to inflammatory diseases.

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    Research 30 of 106

    1. Roles of GasderminA3 in Catagen–Telogen Transition During Hair Cycling Journal of Investigative Dermatology · 2015 · 25 citations
    2. The Immunological Impact of IL-1 Family Cytokines on the Epidermal Barrier Frontiers in Immunology · 2021 · 23 citations
    3. Depletion of <i>Gsdma1/2/3</i> alleviates PMA-induced epidermal hyperplasia by inhibiting the EGFR–Stat3/Akt pathway Journal of Molecular Cell Biology · 2023 · 6 citations
    4. Testosterone levels in relation to oral contraceptive use and the androgen receptor CAG and GGC length polymorphisms in healthy young women Human Reproduction · 2006 · 25 citations
    5. AP-2α/AP-2β transcription factors are key regulators of epidermal homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2023
    6. Hair follicle-specific keratins and their diseases Experimental cell research · 2007 · 138 citations
    7. GSDMA deficiency impairs cutaneous squamous cell carcinoma growth Frontiers in Oncology · 2026
    8. Lichen Planopilaris Elsevier eBooks · 2018
    9. The concealed side of caspases: beyond a killer of cells Cellular and Molecular Life Sciences · 2024 · 13 citations
    10. Aberrant inflammasome activation as a driving force of human autoimmune skin disease Frontiers in immunology · 2023 · 3 citations
    11. Upregulation of interfollicular epidermal and hair infundibulum β-catenin expression in Gsdma3 mutant mice Acta histochemica · 2012 · 11 citations
    12. Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway Oncotarget · 2017 · 11 citations
    13. An Overview of Alopecias Cold Spring Harbor Perspectives in Medicine · 2014 · 53 citations
    14. Mutant laboratory mice with abnormalities in hair follicle morphogenesis, cycling, and/or structure: An update Journal of Dermatological Science · 2012 · 52 citations
    15. Cicatricial Alopecia Research Foundation meeting, May 2016: Progress towards the diagnosis, treatment and cure of primary cicatricial alopecias Experimental Dermatology · 2018 · 22 citations
    16. Regulation of pathophysiological and tissue regenerative functions of MSCs mediated via the WNT signaling pathway (Review) Molecular Medicine Reports · 2021 · 18 citations
    17. Synergistic Wound Healing: Unraveling the Multi-Target Effects of Traditional Chinese Medicine and Its Biomaterials on Chronic Wound Pathways International Journal of Nanomedicine · 2025 · 5 citations
    18. Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study Current Issues in Molecular Biology · 2021 · 1 citations
    19. Immune Microenvironment of Hair Follicles in Tumor Immunotherapy ImmunoTargets and Therapy · 2026
    20. Prevalence of MMP-1 rs1799750 Polymorphism in Androgenetic Alopecia: A Cross-Sectional Study in an Indonesia Population Molecular and Cellular Biomedical Sciences · 2025
    21. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    22. The Hair Follicle Toxicologic pathology · 2016 · 28 citations
    23. Age-induced hair greying - the multiple effects of oxidative stress International Journal of Cosmetic Science · 2013 · 67 citations
    24. Paracrine Secreted Frizzled-Related Protein 4 Inhibits Melanocytes Differentiation in Hair Follicle Stem Cells International · 2017 · 8 citations
    25. Plant Extracts in Skin Care Products 2018 · 5 citations
    26. Oxidative stress and alopecia areata Frontiers in medicine · 2023 · 3 citations
    27. Techniques d'épargne cutanée dans la chirurgie de la gynécomastie Archive ouverte UNIGE (University of Geneva) · 2026
    28. Expression profile analysis of dermal papilla cells mRNA in response to WNT10B treatment Experimental and Therapeutic Medicine · 2019 · 7 citations
    29. Pyroptosis in Alopecia Areata: Synthesizing Emerging Hypotheses and Charting a Path to New Therapies Biomedicines · 2025
    30. Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation American Journal Of Pathology · 2011 · 54 citations