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The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.

The modified Ferriman-Gallwey method is a useful tool for diagnosing hirsutism.

Removing part of the vitamin D receptor stops vitamin D from working properly.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

5% minoxidil works better for hair growth and density, with minor irritation.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

Medium-sized particles penetrate hair follicles better than smaller or larger ones, which could improve delivery of skin treatments.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

FPHL affects hair density and diameter, causing visible hair loss in older women.

Guidelines suggest various treatments for alopecia areata, but leaving it untreated is also an option as 80% cases may recover on their own.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Male and female skin differ in many ways, which could lead to gender-specific skin treatments.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Fungi-produced compounds can change plant root growth.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Finasteride effectively treats frontal hair loss with few side effects.

Experts recommend thorough medical, sexual, and psychosocial assessments for women's sexual dysfunctions, and suggest individualized treatment plans with regular check-ups. They also mention potential use of estrogen and androgen therapy, but with caution due to safety concerns.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Liposomes improve drug delivery and reduce skin irritation in dermatology.

Skin grafts on mice can cause an immune response leading to hair loss, useful for studying human hair loss conditions.

Finasteride helps increase hair growth in men with hair loss.

PEVs improve minoxidil skin penetration, increasing hair growth.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.