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    Glossary Fibroblast Growth Factor 5

    protein that inhibits hair growth by signaling phase transition

    Fibroblast Growth Factor 5 (FGF5) is a protein that plays a crucial role in regulating the hair growth cycle. Specifically, it acts to inhibit hair growth by signaling the transition from the growth phase (anagen) to the regression phase (catagen), which can lead to shorter hair growth periods and potentially contribute to conditions like alopecia.

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    1. Antisense oligonucleotide targeting fibroblast growth factor receptor (FGFR)-1 stimulates cellular activity of hair follicles in an<i>in vitro</i>organ culture system International Journal of Dermatology · 2007 · 7 citations
    2. Structure-guided PEGylated fibroblast growth factor 2 variants accelerate wound healing with improved stability 2020 · 1 citations
    3. Heparin-based sericin hydrogel–encapsulated basic fibroblast growth factor for in vitro and in vivo skin repair Heliyon · 2023 · 22 citations
    4. Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles International Journal of Molecular Medicine · 2011 · 28 citations
    5. Stimulation of mouse vibrissal follicle growth by recombinant human fibroblast growth factor 20 Biotechnology Letters · 2018 · 4 citations
    6. The Potential of Fibroblast Growth Factors to Stimulate Hair Growth In Vitro 2021
    7. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells 2007 · 66 citations
    8. Bioorthogonal Click-Engineered Microneedle Patch Enables Adeno-Associated Virus-Mediated Dermal Acidic Fibroblast Growth Factor Expression for Hair Loss Treatment ACS Nano · 2026
    9. Differentiation of human hair follicle stem cells into endothelial cells induced by vascular endothelial and basic fibroblast growth factors Molecular Medicine Reports · 2013 · 24 citations
    10. Growth factor mimetics for skin regeneration: In vitro profiling of primary human fibroblasts and keratinocytes Archiv der Pharmazie · 2021 · 3 citations
    11. Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro Archives of Dermatological Research · 1987 · 58 citations
    12. Epidermal growth factor and fibroblast growth factor accelerate proliferation of human hair bulb papilla cells and root sheath tibroblasts cultured in vitro British Journal of Dermatology · 1987 · 9 citations
    13. Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells” Journal of Investigative Dermatology · 2007
    14. RGDSP-functionalized peptide hydrogel stimulates growth factor secretion via integrin αv/PI3K/AKT axis for improved wound healing by human amniotic mesenchymal stem cells Frontiers in Bioengineering and Biotechnology · 2024 · 6 citations
    15. Fibroblast Growth Factor-7 and Hair Biology: Bridging Basic Science and Therapeutic Applications Current Issues in Molecular Biology · 2026
    16. Centella asiatica L. Urb. Extracellular Vesicle and Growth Factor Essence for Hair and Scalp Health: A 56-Day Exploratory Randomized Trial Cosmetics · 2025
    17. Immunohistochemical localization of fibroblast growth factor 18 in hair follicles of healthy beagle dogs Veterinary Dermatology · 2011 · 2 citations
    18. Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats Gene · 2015 · 42 citations
    19. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    20. CRISPR/Cas9-mediated Disruption of Fibroblast Growth Factor 5 in Rabbits Results in a Systemic Long Hair Phenotype by Prolonging Anagen Genes · 2020 · 13 citations
    21. De novo follicular regeneration of the skin by wingless int 3 and bone morphogenetic protein 2 genes introduced into dermal fibroblasts and fibroblast growth factor‐2 protein Wound Repair and Regeneration · 2009 · 4 citations
    22. Expression of vascular endothelial growth factor (VEGF) in various compartments of the human hair follicle Archives of Dermatological Research · 1998 · 105 citations
    23. In vivo promoted growth of mice hair follicles by the controlled release of growth factors Biomaterials · 2003 · 60 citations
    24. Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo Cells · 2022 · 4 citations
    25. The potential role of fibroblast‐derived multi‐peptide factors in activation of growth factors and β‐Catenin in hair follicle cells Journal of Cosmetic Dermatology · 2022 · 4 citations
    26. 0855 Topological laser delivery induces efficient regeneration via a transient cell network with super activation of hepatocyte growth factor Journal of Investigative Dermatology · 2025
    27. Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine Dermatologic Surgery · 2005 · 3 citations
    28. Induction of Vascular Endothelial Growth Factor Messenger Ribonucleic Acid Expression in Stored Micrografts by Aminoguanidine Dermatologic Surgery · 2005 · 1 citations
    29. Evaluation of platelet‐rich plasma plus basic fibroblast growth factor combined with minoxidil in the treatment of androgenetic alopecia: A randomized controlled trial Journal of Cosmetic Dermatology · 2023
    30. Effects Of Keratin-Gelatin And Basic Fibroblast Growth Factor-Gelatin Composite Film On Open Wound Healing In Dogs And Cats Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia) · 2007