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Microneedle arrays with nanotechnology show promise for painless drug delivery through the skin but need more research on safety and effectiveness.

Polydopamine is a safe, effective, and permanent hair dye that turns gray hair black in one hour.

Excess male hormones in postmenopausal women can cause health issues and increase the risk of heart disease and diabetes; treatment depends on the cause.

Mindfulness reduces anxiety and depression in skin disease patients; dermatologists and psychiatrists often lack confidence in treating psychodermatological conditions.

Some ovarian tumors can cause masculinization, and it's important to check for various causes when this symptom is present.

Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.

Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Hyaluronic acid is effective for skin rejuvenation and should be a key ingredient in cosmetic products.

A woman's male-like physical changes were caused by two rare ovarian conditions.

3D high-frequency ultrasound can help diagnose skin and hair conditions without invasive biopsies.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

New treatments for relapsing multiple sclerosis are more effective and convenient but have higher risks of serious side effects.

Many women experience sexual dysfunction, but few seek help, and better treatment and medical training are needed.

The document concludes that more research is needed to reduce frequent hospital visits, addiction medicine education improves with specific training, early breast cancer surgery findings are emerging, nipple smears are not very accurate, surgery for older melanoma patients doesn't extend life, a genetic condition in infants can often be treated with one drug, doctors are inconsistent with blood clot medication, a certain gene may protect against cell damage, muscle gene overexpression affects many other genes, and some mitochondrial genes are less active in mice with tumors.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

The document concludes that the acoustic coupler SF-001 is good for skin ultrasound, especially on rough body parts, because it's stable and shows blood vessels well.

Neuroactive steroids show promise for treating mental and neurological disorders by targeting GABA_A receptors.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Diagnosing PCOS in teenagers is hard because its symptoms often look like normal puberty, and there's a need for better diagnosis methods and agreement on criteria.

A woman's hair loss was caused by her husband's testosterone gel and a diabetic man's nail disease led to bone infection, both treated successfully.

A genetic mutation in the DCAF17 gene caused Woodhouse-Sakati syndrome in a Chinese patient from a related family.

Iron nanoparticles made from pumpkin extract effectively treated burns and promoted healing in mice.

Gender-affirming hormone treatments need better patient-focused outcome measurements and standardized data collection.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Progesterone treatment improved seizures in a woman with menstrual cycle-related epilepsy, but a wrong medication worsened her condition.

Eating disorders are serious, often undiagnosed conditions requiring early treatment, with anorexia being the most deadly and binge-eating the most treatable.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Neuroimaging suggests that treatments targeting brain steroids could help control epilepsy, especially types linked to the menstrual cycle.

The document concludes that periocular hair disorders have various causes and treatments, and proper evaluation by specialists is important for management and prognosis.