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    Did you mean Extracellular Signal-Regulated Kinase?
    Glossary Extracellular Signal-Regulated Kinase

    protein that transmits signals from cell surface to DNA

    Extracellular Signal-Regulated Kinase (ERK) is a type of protein kinase that plays a crucial role in the MAPK (Mitogen-Activated Protein Kinase) signaling pathway. It helps transmit signals from the cell surface to the DNA in the cell nucleus, influencing processes like cell division, differentiation, and survival. This pathway is important in various biological functions and can be implicated in conditions like cancer and alopecia when dysregulated.

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    1. Visible red light enhances physiological anagen entry in vivo and has direct and indirect stimulative effects in vitro Lasers in surgery and medicine · 2014 · 35 citations
    2. Hair Growth Stimulation Effect of Centipeda minima Extract: Identification of Active Compounds and Anagen-Activating Signaling Pathways Biomolecules · 2021 · 14 citations
    3. Various Wavelengths of Light-Emitting Diode Light Regulate the Proliferation of Human Dermal Papilla Cells and Hair Follicles via Wnt/β-Catenin and the Extracellular Signal-Regulated Kinase Pathways Annals of Dermatology · 2017 · 33 citations
    4. Extracellular Signal-Regulated Kinase Mediates Ebastine-Induced Human Follicle Dermal Papilla Cell Proliferation BioMed Research International · 2019 · 4 citations
    5. Effect of Puerariae Radix Ethanol Extract on the Proliferation of Human Dermal Papilla Cells Journal of Physiology & Pathology in Korean Medicine · 2017 · 3 citations
    6. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells Biomolecules & therapeutics · 2021 · 8 citations
    7. Lentiviral Arrays for Live-cell Dynamic Monitoring of Gene and Pathway Activity During Stem Cell Differentiation Molecular therapy · 2014 · 13 citations
    8. An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice ( <i>Acomys</i> ) Science Advances · 2023 · 1 citations
    9. Hair Growth Effect and the Mechanisms of Rosa rugosa Extract in DHT-Induced Alopecia Mice Model International Journal of Molecular Sciences · 2024
    10. Regulation and Role of GLI1 in Cutaneous Squamous Cell Carcinoma Pathogenesis Frontiers in genetics · 2019 · 6 citations
    11. Hair growth–promoting effects of Enz_MoriL on human dermal papilla cells through modulation of the Wnt/β-Catenin and JAK-STAT signaling pathways Archives of dermatological research · 2024
    12. Cell wall-associated ROOT HAIR SPECIFIC 10, a proline-rich receptor-like kinase, is a negative modulator of Arabidopsis root hair growth Journal of Experimental Botany · 2016 · 33 citations
    13. Cell fate decisions: emerging roles for metabolic signals and cell morphology EMBO Reports · 2017 · 100 citations
    14. Extracellular matrix sensing by FERONIA and Leucine‐Rich Repeat Extensins controls vacuolar expansion during cellular elongation in <i>Arabidopsis thaliana</i> The EMBO Journal · 2019 · 172 citations
    15. The Critical Roles of Serum/Glucocorticoid-Regulated Kinase 3 (SGK3) in the Hair Follicle Morphogenesis and Homeostasis American Journal of Pathology · 2006 · 9 citations
    16. MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling Developmental Cell · 2010 · 118 citations
    17. TOR tour to auxin EMBO journal · 2013 · 32 citations
    18. Mathematical Modeling and Inference of Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Cell Signaling Pathways International Journal of Molecular Sciences · 2024 · 3 citations
    19. Type II Keratins Are Phosphorylated on a Unique Motif during Stress and Mitosis in Tissues and Cultured Cells Molecular Biology of the Cell · 2002 · 80 citations
    20. The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth 2018 · 109 citations
    21. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    22. Comparative analysis of stemness between dermal papilla cells and human dermalstem/progenitor cells Cellular and Molecular Biology · 2025
    23. Type I Keratin 17 Protein Is Phosphorylated on Serine 44 by p90 Ribosomal Protein S6 Kinase 1 (RSK1) in a Growth- and Stress-dependent Fashion 2011 · 30 citations
    24. Dysregulated behaviour of hair follicle stem cells triggers alopecia and provides potential therapeutic targets Experimental Dermatology · 2022 · 3 citations
    25. Adipose tissue protects against skin photodamage through CD151- and AdipoQ- EVs Cell Communication and Signaling · 2024
    26. The JAK/STAT signaling pathway: from bench to clinic Signal Transduction and Targeted Therapy · 2021 · 489 citations
    27. CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis Nature Communications · 2025
    28. Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo Journal of Biological Chemistry · 1997 · 52 citations
    29. Tribuloside acts on the PDE/cAMP/PKA pathway to enhance melanogenesis, melanocyte dendricity and melanosome transport Journal of ethnopharmacology · 2023
    30. Minoxidil prevents 3,4-methylenedioxymethamphetamine-induced serotonin depletions: role of mitochondrial ATP-sensitive potassium channels, Akt and ERK Journal of Neurochemistry · 2008 · 22 citations