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Gender-affirming hormone therapy improves physical performance in trans men to the level of cisgender men, while in trans women, it increases fat mass and decreases muscle mass, with no advantage in physical performance after 2 years.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Pregnancy can cause various skin changes and diseases, requiring careful treatment to protect the baby.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

The medications 5α-reductase inhibitors and spironolactone are generally safe for breast cancer patients on endocrine therapies and do not significantly increase breast cancer risk.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Treating hirsutism in women often requires a mix of medications and cosmetic methods for best results.

Diagnosing and treating PCOS is complex due to differing criteria and requires a team approach.

Exposure to certain sex hormones can increase health risks, while some hormone therapies may offer benefits for specific conditions.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The conclusion is that thorough investigation of hypertension and hormonal dysfunctions is important, and there may be a link between these conditions and cancer.

The paper suggests that a decrease in estrogen receptor activity may cause sexual dysfunction syndromes and proposes hormonal treatments.

Hormones like testosterone and estrogen significantly affect hair growth and structure.

Hormones affect skin aging, and treatments targeting hormonal balance may improve skin health.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

A breast cancer patient had lasting hair loss after chemotherapy, which improved with minoxidil treatment.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Using 3% topical minoxidil can help women with hair loss, but more research is needed.

Transgender men on testosterone therapy need ongoing gynecologic care due to potential cancer risks.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.