26 citations,
April 1998 in “Journal of Investigative Dermatology” The study developed a novel in vivo model using transgenic mice to evaluate agents that protect against UVA-induced photoaging. This model used a human elastin promoter linked to a CAT reporter gene to measure elastin gene induction. It showed that PUVA treatment significantly increased promoter activation, which was reduced by sunscreens, particularly those with SPF 15 and UVA filters. The combination sunscreen provided the greatest protection, reducing CAT activity to near baseline levels. This model proved effective for rapidly identifying and comparing compounds that protect against UVA-induced photoaging, despite differences between murine and human skin responses.
25 citations,
January 2015 in “Advances in Psychosomatic Medicine” Many skin patients also have mental health issues, and doctors should treat both together.
24 citations,
April 2008 in “Fertility and sterility” Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.
24 citations,
September 2001 in “Journal of The American Academy of Dermatology” Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.
24 citations,
May 1995 in “Journal of Adolescent Health” Inner city teens had high retention rates for the contraceptive implant, especially those with a history of abortion.
24 citations,
May 1982 in “Biochemical Pharmacology” These drugs cause hair growth without affecting testosterone or adrenal hormones.
23 citations,
June 2017 in “Rejuvenation Research” Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.
22 citations,
September 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” The study's results on the effectiveness of low-dose IL-2 for alopecia areata and its impact on immune cells were not provided.
19 citations,
February 2017 in “Journal of radiation research” High-dose radiation speeds up aging in skin stem cells.
19 citations,
November 2015 in “Radiation Oncology” Hippocampus sparing whole brain radiation therapy prevents hair loss and preserves cognitive function.
19 citations,
October 2014 in “Veterinary Dermatology” Dermoscopy is a good, noninvasive way to see normal cat skin structures and could be useful for check-ups.
19 citations,
November 2010 in “PubMed” New genetic insights have improved understanding of hair loss, leading to a new test and treatments, but more research is needed on the test and laser comb effectiveness.
18 citations,
June 2017 in “Journal of the neurological sciences” Using 5 alpha reductase inhibitors may increase dementia risk in the first two years.
18 citations,
March 2017 in “International clinical psychopharmacology” Inositol was not more effective than a placebo in treating trichotillomania.
18 citations,
September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
16 citations,
July 2016 in “Veterinary Dermatology” Dermoscopy is useful for diagnosing hair loss patterns in dogs.
15 citations,
February 2014 in “BMC Research Notes” The X5 Hairlaser might help treat male hair loss, but more research is needed.
14 citations,
December 2018 in “The American journal of pathology” Activating Nrf2 in skin cells speeds up wound healing by increasing the growth of certain stem cells.
14 citations,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
14 citations,
November 2009 in “Dermatologic Surgery” Laser hair removal can cause severe allergic reactions.
13 citations,
January 2014 in “Journal of Veterinary Internal Medicine” The cat's hypothyroidism was successfully managed with levothyroxine, leading to a stable condition.
13 citations,
August 2012 in “Journal of the American Academy of Dermatology” A rare scalp condition causing hair loss and cysts in young men can be treated effectively with a specific steroid injection.
13 citations,
July 1996 in “Annals of Internal Medicine” International medical graduates outperformed U.S. graduates on an internal medicine exam.
11 citations,
October 2021 in “Journal of The European Academy of Dermatology and Venereology” Topical finasteride is an effective and safer treatment for male hair loss.
11 citations,
January 2020 in “Skin appendage disorders” Low-level laser therapy safely and effectively improves hair growth and coverage for male and female pattern hair loss.
11 citations,
August 2019 in “PubMed” Hirsutism in women is mostly caused by polycystic ovary syndrome and idiopathic hyperandrogenism.
11 citations,
August 2012 in “BMJ case reports” Ban Tu Wan, a Chinese herbal supplement, can cause severe liver damage.
11 citations,
January 2012 in “PubMed” Bimatoprost can help grow eyebrow hair.
11 citations,
March 2010 in “International Journal of Andrology” Finasteride 1-mg doesn't harm sperm or pregnancy chances.
10 citations,
February 2019 in “The New England Journal of Medicine” Removing lymph nodes does not improve survival for advanced ovarian cancer and may cause more complications.