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    Glossary Epithelial-Mesenchymal Transition

    cells change from stationary epithelial to mobile mesenchymal

    Epithelial-Mesenchymal Transition (EMT) is a biological process where epithelial cells, which are usually stationary and form tight layers, transform into mesenchymal cells, which are more mobile and can migrate. This process is crucial in various physiological contexts, such as wound healing and embryonic development, but it also plays a role in pathological conditions like cancer metastasis and fibrosis.

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    1. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    2. WNT5A drives interleukin-6-dependent epithelial–mesenchymal transition via the JAK/STAT pathway in keloid pathogenesis Burns & Trauma · 2022 · 56 citations
    3. Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes Wound repair and regeneration · 2015 · 46 citations
    4. Expression of Snail1 in the fibrotic dermis of postmenopausal frontal fibrosing alopecia: possible involvement of an epithelial-mesenchymal transition and a review of the Japanese patients British Journal of Dermatology · 2010 · 29 citations
    5. Peroxisome proliferator-activated receptor-γ signalling protects hair follicle stem cells from chemotherapy-induced apoptosis and epithelial–mesenchymal transition 2021 · 19 citations
    6. Drugs targeting epithelial–mesenchymal transition molecules for treatment of lichen planopilaris Clinical and experimental dermatology · 2022 · 3 citations
    7. Epithelial–mesenchymal transition in cutaneous fibrosis disease: from mechanisms to therapy Frontiers in Immunology · 2026
    8. Inhibition of Cholesterol Biosynthesis Modulates Epithelial-Mesenchymal Transition in Primary Cicatricial Alopecia Through TGFβ and Angiotensin Receptors Journal of Endocrinology and Reproduction · 2023
    9. Epithelial Mesenchymal Transition and Tissue Healing Journal of Medical Histology · 2019
    10. 269 The PPAR-γ modulator, N-acetyl-GED, protects from epithelial-mesenchymal-transition to human hair follicles: Potential relevance for scarring alopecia 2017
    11. Epithelial–Mesenchymal Plasticity and Endothelial–Mesenchymal Transition in Cutaneous Wound Healing Cold Spring Harbor Perspectives in Biology · 2022 · 31 citations
    12. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    13. Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading Developmental Dynamics · 2017 · 141 citations
    14. Epithelial-to-Mesenchymal Stem Cell Transition in a Human Organ: Lessons from Lichen Planopilaris Journal of Investigative Dermatology · 2017 · 71 citations
    15. Epithelial elements in superficial angiomyxomas: mimicry of adnexal development, and mesenchymal‐to‐epithelial transition Histopathology · 2025
    16. 1323 Human dermal fibroblasts and mast cell populations are altered in hidradenitis suppurativa, with epithelial-mesenchymal-transition signals ameliorated by spleen tyrosine kinase antagonism. Journal of Investigative Dermatology · 2023
    17. hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis Aging · 2023 · 3 citations
    18. Equine Hoof Stratum Internum K14+CD105+ Progenitor Cells: Culture, Characterization, and Model of Epithelial to Mesenchymal Transition 2019
    19. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018 · 80 citations
    20. 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    21. ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    22. Zwischen Tradition und Innovation Historische Plätze in der Bundesrepublik Deutschland nach 1945 2004 · 1 citations
    23. An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation EMBO Reports · 2018 · 30 citations
    24. LB999 Role of transcription factor Ovol2 in skin epithelial regeneration and repair Journal of Investigative Dermatology · 2017
    25. 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia Journal of Investigative Dermatology · 2018
    26. Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture Nature cell biology · 2024 · 2 citations
    27. Wnt1/βcatenin injury response activates the epicardium and cardiac fibroblasts to promote cardiac repair The EMBO Journal · 2011 · 248 citations
    28. Regeneration of Dermis: Scarring and Cells Involved Cells · 2019 · 176 citations
    29. TGF-β family signaling in stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 132 citations
    30. PAK4 signaling in health and disease: defining the PAK4–CREB axis Experimental & Molecular Medicine · 2019 · 81 citations