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    Glossary Epithelial Stem Cell Differentiation

    process where stem cells become specialized skin or hair cells

    Epithelial stem cell differentiation is the process by which unspecialized stem cells in the epithelial tissue develop into specialized cell types that make up the skin, hair, and lining of organs. This process is crucial for tissue repair, regeneration, and maintaining the normal function of these tissues.

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    1. Hairless and Wnt Signaling: Allies in Epithelial Stem Cell Differentiation Cell Cycle · 2006 · 74 citations
    2. Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro European Journal of Cell Biology · 2010 · 42 citations
    3. Corrigendum to “Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro” [Eur. J. Cell Biol. (2010) 769–777] European Journal of Cell Biology · 2012 · 1 citations
    4. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    5. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    6. CD49fhigh Defines a Distinct Skin Mesenchymal Stem Cell Population Capable of Hair Follicle Epithelial Cell Maintenance 2019 · 11 citations
    7. 1358 PRC1 fine-tunes gene repression and activation to safeguard skin epithelium development and stem cell specification Journal of Investigative Dermatology · 2018 · 1 citations
    8. Local Microenvironment Provides Important Cues for Cell Differentiation in Lingual Epithelia PloS one · 2012 · 6 citations
    9. Transcriptional profiling of putative human epithelial stem cells BMC Genomics · 2008 · 16 citations
    10. Cloning and induced differentiation of skin stem cells in vitro 2010
    11. Histone H3 K4/9/27 Trimethylation Levels Affect Wound Healing and Stem Cell Dynamics in Adult Skin Stem Cell Reports · 2019 · 26 citations
    12. 136 Physiological function of Krox20 (Egr2) in epithelial stem cells Journal of Investigative Dermatology · 2021
    13. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    14. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    15. 448 Physiological function of krox20 (Egr2) in epithelial stem cells 2022
    16. The Dynamic Duo: Niche/Stem Cell Interdependency Stem Cell Reports · 2015 · 31 citations
    17. Cutaneous Epithelial Stem Cells Elsevier eBooks · 2013
    18. 25 Years of Epidermal Stem Cell Research Journal of Investigative Dermatology · 2012 · 55 citations
    19. Signaling in the stem cell niche: regulating cell fate, function and plasticity Development · 2018 · 139 citations
    20. Wnt signaling induces epithelial differentiation during cutaneous wound healing Organogenesis · 2015 · 66 citations
    21. Retinoic acids shift skin stem cell fate Journal of Investigative Dermatology · 2026
    22. Building Epithelial Tissues from Skin Stem Cells Cold Spring Harbor Symposia on Quantitative Biology · 2008 · 84 citations
    23. The Progress of Epidermal Stem Cell Research 2010
    24. Clonal analysis of stem cells in differentiation and disease Current Opinion in Cell Biology · 2016 · 11 citations
    25. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    26.  Np63 Regulates Stem Cell Dynamics in the Mammalian Olfactory Epithelium Journal of Neuroscience · 2011 · 93 citations
    27. Hair Follicle Stem Cell SLC3A2 Regulates Epithelial Regenerative Properties Journal of Investigative Dermatology · 2025
    28. The Potential Reversible Transition between Stem Cells and Transient-Amplifying Cells: The Limbal Epithelial Stem Cell Perspective Cells · 2024 · 1 citations
    29. Population and Individual Stem Cell Dynamics in the Olfactory Epithelium eScholarship (California Digital Library) · 2016
    30. Apoptotic cells may drive cell death in hair follicles during their regression cycle Oncotarget · 2023