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    Glossary Epithelial Sac

    small, enclosed structure of epithelial cells around hair follicle

    An epithelial sac is a small, enclosed structure composed of epithelial cells, which are cells that line the surfaces and cavities of the body. In the context of hair biology, an epithelial sac can refer to the structure that surrounds the developing hair follicle, playing a crucial role in the formation and growth of hair. This sac provides a protective environment and supplies necessary nutrients to the growing hair shaft.

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    Research 30 of 1000+

    1. Nestin as a marker of unipotent epithelial progenitor cell differentiation into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    2. Epithelial–mesenchymal transition in keloid tissues and TGF‐β1–induced hair follicle outer root sheath keratinocytes Wound repair and regeneration · 2015 · 46 citations
    3. K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1 Journal of Investigative Dermatology · 2003 · 130 citations
    4. A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle Journal of Investigative Dermatology · 2002 · 86 citations
    5. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    6. Nestin as a marker of unipotent epithelial progenitor cells differentiate into outer root sheath keratinocytes in embryonic and adult hair follicles Research Square (Research Square) · 2022
    7. ILK modulates epithelial polarity and matrix formation in hair follicles Molecular biology of the cell · 2013 · 22 citations
    8. Progenitor-derived endothelin controls dermal sheath contraction for hair follicle regression Nature cell biology · 2023 · 5 citations
    9. Hair-follicle dermal papilla and sheath fibroblasts provide a supportive microenvironment for human skin regeneration 2017 · 3 citations
    10. The Growth of Human Dermal Papilla Cells and Dermal Sheath Cells in Vitro Chinese Journal of Dermatology · 2001
    11. Sex Hormones and Antiandro Growth of Dermal Papilla H ens Influence In Vitro Ce Is and Outer Root Sheath Keratinocytes of Human Hair Follicles 1993
    12. Manganese Ethylene Bis(Maneb)-Induced Degeneration of Hair Follicle Epithelia in the Dosal Skin of WBN/ILA-Ht Rats. Journal of Toxicologic Pathology · 1998 · 5 citations
    13. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles Differentiation · 1988 · 248 citations
    14. A Human Folliculoid Microsphere Assay for Exploring Epithelial– Mesenchymal Interactions in the Human Hair Follicle 2008 · 71 citations
    15. Requirement of zinc transporter ZIP10 for epidermal development: Implication of the ZIP10–p63 axis in epithelial homeostasis Proceedings of the National Academy of Sciences · 2017 · 59 citations
    16. The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells Journal of Dermatological Science · 2001 · 47 citations
    17. Expression patterns of MITF during human cutaneous embryogenesis: evidence for bulge epithelial expression and persistence of dermal melanoblasts Journal of cutaneous pathology · 2008 · 43 citations
    18. Heparanase 1: a key participant of inner root sheath differentiation program and hair follicle homeostasis Experimental Dermatology · 2008 · 22 citations
    19. Epithelial expression of the hormone leptin by bovine skin European journal of histochemistry · 2019 · 18 citations
    20. Progenitor cells expressing nestin, a neural crest stem cell marker, differentiate into outer root sheath keratinocytes Veterinary Dermatology · 2019 · 12 citations
    21. Spatiotemporal atlas resolves the mesenchymal-epithelial stem cell axis governing human hair follicle aging and pathology bioRxiv (Cold Spring Harbor Laboratory) · 2026
    22. Keratin 15 Expression in Stratified Epithelia: Downregulation in Activated Keratinocytes Journal of Investigative Dermatology · 1999 · 198 citations
    23. Keratinocyte differentiation in psoriatic scalp: morphology and expression of epithelial keratins British Journal of Dermatology · 2006 · 63 citations
    24. Interaction between dermal papilla cells and follicular epithelial cells in vitro: effect of androgen. PubMed · 1995 · 48 citations
    25. Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle. PubMed · 1990 · 44 citations
    26. Wnt-10b promotes differentiation of skin epithelial cells in vitro Biochemical and Biophysical Research Communications · 2006 · 36 citations
    27. Experimental Modulation of the Differentiated Phenotype of Keratinocytes from Epidermis and Hair Follicle Outer Root Sheath and Matrix Cells Annals of the New York Academy of Sciences · 1991 · 31 citations
    28. Fabrication and characterization of epithelial scaffolds for hair follicle regeneration Tissue Engineering and Regenerative Medicine · 2012 · 4 citations
    29. Interaction between dermal papilla cells and follicular epithelial cells in vitro: effect of androgen 2006 · 4 citations
    30. A new in vitro culture system to produce a fully differentiated epidermis from human hair follicle outer root sheath cells 1989 · 2 citations