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    Glossary Epithelial Proliferation

    process where skin cells multiply and increase in number

    Epithelial proliferation refers to the process by which epithelial cells, which form the outer layer of skin and line various organs and structures in the body, multiply and increase in number. This process is crucial for wound healing, tissue regeneration, and maintaining the integrity of barriers against pathogens. In the context of hair, epithelial proliferation is important for the growth and regeneration of hair follicles.

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    1. β1 Integrin Signaling Maintains Human Epithelial Progenitor Cell Survival In Situ and Controls Proliferation, Apoptosis and Migration of Their Progeny PLoS ONE · 2013 · 20 citations
    2. 1458 EMT-inhibiting transcription factor Ovol2 regulates directional cell migration and proliferation in adult skin epithelia Journal of Investigative Dermatology · 2018
    3. Peroxisome proliferator-activated receptor-γ signalling protects hair follicle stem cells from chemotherapy-induced apoptosis and epithelial–mesenchymal transition 2021 · 19 citations
    4. An Ovol2‐Zeb1 transcriptional circuit regulates epithelial directional migration and proliferation EMBO Reports · 2018 · 30 citations
    5. The Effects of Negative Pressure by External Tissue Expansion Device on Epithelial Cell Proliferation, Neo-Vascularization and Hair Growth in a Porcine Model PLoS ONE · 2016 · 16 citations
    6. 1434 Epithelially derived MPZL3 negatively regulates murine and human sebaceous gland size and sebocyte proliferation Journal of Investigative Dermatology · 2023
    7. Squamous epithelial proliferation induced by walleye dermal sarcoma retrovirus cyclin in transgenic mice Proceedings of the National Academy of Sciences · 2000 · 28 citations
    8. Biological actions of oligomeric procyanidins: Proliferation of epithelial cells and hair follicle growth 2001 · 8 citations
    9. Dihydroartemisinin attenuates benign prostatic hyperplasia in rats by inhibiting prostatic epithelial cell proliferation Annals of Translational Medicine · 2021 · 4 citations
    10. Runx1 Role in Epithelial and Cancer Cell Proliferation Implicates Lipid Metabolism and Scd1 and Soat1 Activity Stem cells · 2018 · 24 citations
    11. VEGF165 modulates proliferation, adhesion, migration and differentiation of cultured human outer root sheath cells from central hair follicle epithelium through VEGFR-2 activation in vitro Journal of Dermatological Science · 2013 · 35 citations
    12. Receptor activator of NF-κB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit Proceedings of the National Academy of Sciences of the United States of America · 2011 · 60 citations
    13. Cyclosporin A Promotes Hair Epithelial Cell Proliferation and Modulates Protein Kinase C Expression and Translocation in Hair Epithelial Cells Journal of Investigative Dermatology · 2001 · 45 citations
    14. Divergent proliferation patterns of distinct human hair follicle epithelial progenitor niches in situ and their differential responsiveness to prostaglandin D2 Scientific Reports · 2017 · 21 citations
    15. Procyanidin Oligomers Selectively and Intensively Promote Proliferation of Mouse Hair Epithelial Cells In Vitro and Activate Hair Follicle Growth In Vivo11The authors disclosed conflict of interest. 1999 · 79 citations
    16. Polyphenols from the Heartwood of<i>Cercidiphyllum japonicum</i>and their Effects on Proliferation of Mouse Hair Epithelial Cells Planta medica · 2002 · 26 citations
    17. Peroxisome Proliferator–Activated Receptor-γ−Mediated Signaling Regulates Mitochondrial Energy Metabolism in Human Hair Follicle Epithelium Journal of Investigative Dermatology · 2018 · 17 citations
    18. The germinative epithelium of sheep vibrissae and wool follicles has extensive proliferative potential but is dependent on the dermal papilla International journal of trichology · 2012 · 1 citations
    19. Pigment epithelium‑derived factor short peptides facilitate full‑thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation Experimental and Therapeutic Medicine · 2017 · 6 citations
    20. The Krüppel-like Factor Epiprofin Is Expressed by Epithelium of Developing Teeth, Hair Follicles, and Limb Buds and Promotes Cell Proliferation Journal of Biological Chemistry · 2003 · 88 citations
    21. PD59-09 PHOSPHODIESTERASE INHIBITORS COULD REVERSE THE PROLIFERATION OF BPH EPITHELIAL CELLS INDUCED BY CD8+ T CELLS IN LOW ANDROGEN CONDITION The Journal of Urology · 2018
    22. Wnt7a can up-regulates cell adhesion related protein fibronectin expression and promotes cell proliferation in corneal epithelial cells 2023
    23. The Insulin-like Growth Factor 1 Receptor Is Expressed by Epithelial Cells with Proliferative Potential in Human Epidermis and Skin Appendages: Correlation of Increased Expression with Epidermal Hyperplasia Journal of Investigative Dermatology · 1996 · 128 citations
    24. Characterisation of cell cycle arrest and terminal differentiation in a maximally proliferative human epithelial tissue: Lessons from the human hair follicle matrix European Journal of Cell Biology · 2017 · 30 citations
    25. Context-dependent effect of sPLA2-IIA induced proliferation on murine hair follicle stem cells and human epithelial cancer EBioMedicine · 2019 · 13 citations
    26. hsa_circ_0002980 prevents proliferation, migration, invasion, and epithelial-mesenchymal transition of liver cancer cells through microRNA-1303/cell adhesion molecule 2 axis Aging · 2023 · 3 citations
    27. Modulation of AR-FGF-2-TGF beta Axis by Cosmos caudatus Suppresses Prostatic Epithelial Proliferation in a BPH Rat Model: A Comparative Study with Finasteride Journal of Multidisciplinary Applied Natural Science · 2026
    28. Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth Developmental Biology · 1983 · 124 citations
    29. Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway PLOS ONE · 2011 · 38 citations
    30. Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases Trends in Molecular Medicine · 2018 · 80 citations