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    Glossary Epithelialization

    process of new skin cells covering a wound

    Epithelialization is the process by which new epithelial cells form and migrate to cover a wound or damaged tissue, creating a protective barrier. This is a crucial step in wound healing, as it helps to restore the integrity of the skin or mucous membranes, preventing infection and further injury.

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    Research 30 of 1000+

    1. Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis 2012 · 47 citations
    2. Autonomous, Moisture‐Driven Flexible Electrogenerative Dressing for Enhanced Wound Healing Advanced Materials · 2025 · 23 citations
    3. A 3D-printed hydrogel scaffold promotes infected diabetic wound repair via anti-inflammation, angiogenesis, and extracellular matrix remodeling Materials & Design · 2026
    4. Acellular dermal matrix hydrogels promote healing of radiation-induced skin injury in a rat model Journal of Materials Chemistry B · 2024 · 8 citations
    5. Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire 2017 · 40 citations
    6. The expanding significance of keratin intermediate filaments in normal and diseased epithelia Current opinion in cell biology · 2012 · 186 citations
    7. Keratins in health and cancer: more than mere epithelial cell markers Oncogene · 2010 · 438 citations
    8. eLife assessment: Decoding the complexity of delayed wound healing following Enterococcus faecalis infection 2024
    9. Choreographing Immunity in the Skin Epithelial Barrier Immunity · 2019 · 57 citations
    10. Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages Experimental Cell Research · 2014 · 14 citations
    11. Scaffolds for epithelial and hair follicle regeneration Elsevier eBooks · 2019 · 1 citations
    12. Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis Genes & Development · 2008 · 102 citations
    13. Cell Polarization Defects in Early Heart Development Circulation Research · 2007 · 9 citations
    14. Adenomatous Polyposis Coli (APC) Is Required for Normal Development of Skin and Thymus PLoS Genetics · 2006 · 184 citations
    15. CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation Journal of Cellular and Molecular Medicine · 2025 · 3 citations
    16. Immune-Epithelial Cross Talk in Regeneration and Repair Annual Review of Immunology · 2023 · 52 citations
    17. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns Developmental Biology · 2017 · 33 citations
    18. Epigenetic orchestration of RNA m<sup>6</sup>A methylation in wound healing and post-wound events International Journal of Biological Sciences · 2025 · 3 citations
    19. Innervated Biomaterials for Improved Cutaneous Wound Healing: A Review of Recent Advancements and Future Prospects International Journal of Nanomedicine · 2025 · 2 citations
    20. Hair-follicle associated pluripotent (HAP)-cell-sheet implantation enhanced wound healing in diabetic db/db mice PLoS ONE · 2024 · 1 citations
    21. Smart hydrogel dressings for advanced wound healing: from biomaterial design to microenvironment modulation Frontiers in Materials · 2026
    22. Hair follicle organoids: advances in construction, applications, and translational challenges Frontiers in Cell and Developmental Biology · 2026
    23. Aged differentiated cells reverse into native stemness-like state by niche cytokines to sustain lifelong homeostasis and tissue repair Nature Communications · 2026
    24. ARHGEF3 Regulates Hair Follicle Morphogenesis 2024
    25. Mechanical force drives the initial mesenchymal-epithelial interaction during skin organoid development Theranostics · 2023
    26. 1380 PPAR-γ modulation as a novel therapeutic strategy for scarring alopecia Journal of Investigative Dermatology · 2018
    27. Proceedings of the Heinz Maurer-Symposium “Review and Preview in Science for Healthy Skin” June 28th 2014, Jakobsberg, Boppard, Germany Aktuelle Dermatologie · 2014
    28. Immunopathogenesis of Primary Cicatricial Alopecia Research Portal (King's College London) · 2013
    29. Activin B Promotes Epithelial Wound Healing In Vivo through RhoA-JNK Signaling Pathway PLOS ONE · 2011 · 38 citations
    30. Human adipose tissue-derived small extracellular vesicles promote soft tissue repair through modulating M1-to-M2 polarization of macrophages Stem Cell Research & Therapy · 2023 · 2 citations