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    Glossary Epithelial Stem Cells

    cells that regenerate and repair skin and hair follicles

    Epithelial Stem Cells are a type of stem cell found in the epithelial tissues, which line the surfaces and cavities of organs and structures throughout the body, including the skin and hair follicles. These cells have the unique ability to self-renew and differentiate into various specialized cell types, playing a crucial role in tissue repair, regeneration, and maintaining the integrity of the epithelial layers.

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    Research 30 of 1000+

    1. Characterization of Epithelial Hair Follicle Stem Cells in Lichen Planopilaris and Folliculitis Decalvans Through Keratin 19 Expression American Journal of Dermatopathology · 2025
    2. 382 Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    3. ESDR382 - Environmental pathobiology of frontal fibrosing alopecia (FFA): Does linalool promote FFA development and progression by inducing epithelial hair follicle stem cell damage and MICA expression in the bulge? 2022
    4. Interfollicular epidermal stem-like cells for the recreation of the hair follicle epithelial compartment Stem cell research & therapy · 2021 · 14 citations
    5. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations Journal of Clinical Investigation · 2011 · 178 citations
    6. Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile ˜The œFASEB journal · 2007 · 45 citations
    7. Peroxisome proliferator-activated receptor-γ signalling protects hair follicle stem cells from chemotherapy-induced apoptosis and epithelial–mesenchymal transition 2021 · 19 citations
    8. Hair follicle epithelial stem cells contribute to interfollicular epidermis during homeostasis JCI Insight · 2025 · 1 citations
    9. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    10. Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells Stem Cells · 2008 · 162 citations
    11. Pigment epithelium‑derived factor short peptides facilitate full‑thickness cutaneous wound healing by promoting epithelial basal cell and hair follicle stem cell proliferation Experimental and Therapeutic Medicine · 2017 · 6 citations
    12. Spatiotemporal atlas resolves the mesenchymal-epithelial stem cell axis governing human hair follicle aging and pathology bioRxiv (Cold Spring Harbor Laboratory) · 2026
    13. 09-P006 Epithelial–mesenchymal interactions promote hair follicle neogenesis and a new stem cell niche in adult corneal epithelium Mechanisms of Development · 2009
    14. Human epithelial hair follicle stem cells and their progeny: Current state of knowledge, the widening gap in translational research and future challenges BioEssays · 2014 · 106 citations
    15. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    16. Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro European Journal of Cell Biology · 2010 · 42 citations
    17. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    18. Multi-potentiality of a new immortalized epithelial stem cell line derived from human hair follicles In vitro cellular & developmental biology. Animal · 2008 · 34 citations
    19. Corneal epithelial‐like transdifferentiation of hair follicle stem cells is mediated by pax6 and β‐catenin/Lef‐1 Cell Biology International · 2009 · 20 citations
    20. Human epithelial stem cell survival within their niche requires “tonic” cannabinoid receptor 1‐signalling—Lessons from the hair follicle Experimental Dermatology · 2021 · 14 citations
    21. Limbal microenvironment can induce transdifferentiation of hair follicle stem cells into corneal epithelial‐like cells Acta Ophthalmologica · 2008
    22. Comparison of growth status of epithelial stem cells derived from plucked hair follicle between different culture conditions Journal of Jilin University · 2009
    23. Mapping the expression of epithelial hair follicle stem cell‐related transcription factors LHX2 and SOX9 in the human hair follicle Experimental Dermatology · 2015 · 33 citations
    24. Tooth, hair and claw: Comparing epithelial stem cell niches of ectodermal appendages Experimental Cell Research · 2014 · 14 citations
    25. N1-methylspermidine, a stable spermidine analog, prolongs anagen and regulates epithelial stem cell functions in human hair follicles Archives of dermatological research · 2015 · 13 citations
    26. 549 Temporary cell cycle arrest in human scalp hair follicles and their epithelial stem cells by ALRN-6924: A novel strategy to selectively protect p53-wildtype cells against paclitaxel-induced alopecia Journal of Investigative Dermatology · 2022 · 1 citations
    27. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    28. Abstract LB-039: Chronic inflammation-mediated contribution of bone marrow-derived epithelial cells and hair follicle stem cells to development of cutaneous neoplasms Cancer Research · 2019
    29. Abstract LB-039: Chronic inflammation-mediated contribution of bone marrow-derived epithelial cells and hair follicle stem cells to development of cutaneous neoplasms Tumor Biology · 2019
    30. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006 · 176 citations