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    Glossary Epithelium

    type of tissue covering body surfaces and lining cavities

    Epithelium is a type of tissue that forms the outer layer of the body's surfaces and lines internal organs and cavities. It acts as a protective barrier and is involved in functions such as absorption, secretion, and sensation. For example, the skin's outer layer and the lining of the digestive tract are made up of epithelial cells.

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    Research 30 of 1000+

    1. Dedifferentiation of committed epithelial cells into stem cells in vivo Nature · 2013 · 551 citations
    2. Epithelial Stem Cells: Turning over New Leaves Cell · 2007 · 508 citations
    3. Keratin cytoskeletons in epithelial cells of internal organs Proceedings of the National Academy of Sciences · 1979 · 482 citations
    4. Plasticity of epithelial stem cells in tissue regeneration Science · 2014 · 479 citations
    5. Epithelial barrier function: assembly and structural features of the cornified cell envelope BioEssays · 2002 · 425 citations
    6. Molecular Dissection of Mesenchymal–Epithelial Interactions in the Hair Follicle PLoS biology · 2005 · 417 citations
    7. Keratin 15 Promoter Targets Putative Epithelial Stem Cells in the Hair Follicle Bulge Journal of Investigative Dermatology · 2003 · 387 citations
    8. Defining the impact of β-catenin/Tcf transactivation on epithelial stem cells Genes & development · 2005 · 384 citations
    9. Onset of Keratin 17 Expression Coincides with the Definition of Major Epithelial Lineages during Skin Development The Journal of Cell Biology · 1998 · 318 citations
    10. Molecular Control of Epithelial–Mesenchymal Interactions During Hair Follicle Cycling 2003 · 277 citations
    11. Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration Cell · 2011 · 260 citations
    12. Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis Developmental dynamics · 1998 · 252 citations
    13. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles Differentiation · 1988 · 248 citations
    14. Lichen planopilaris is characterized by immune privilege collapse of the hair follicle's epithelial stem cell niche The Journal of Pathology · 2013 · 220 citations
    15. Epithelial-Mesenchymal Micro-niches Govern Stem Cell Lineage Choices Cell · 2017 · 214 citations
    16. Androgen‐inducible TGF‐β1 from balding dermal papilla cells inhibits epithelial cell growth: a clue to understanding paradoxical effects of androgen on human hair growth ˜The œFASEB journal · 2002 · 190 citations
    17. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues II. Concomitant and mutually exclusive synthesis of trichocytic and epithelial cytokeratins in diverse human and bovine tissues (hair follicle, nail bed and matrix, lingual papilla, thymic reticulum) Differentiation · 1988 · 187 citations
    18. The expanding significance of keratin intermediate filaments in normal and diseased epithelia Current opinion in cell biology · 2012 · 186 citations
    19. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations Journal of Clinical Investigation · 2011 · 178 citations
    20. Bone Morphogenetic Protein Signaling Inhibits Hair Follicle Anagen Induction by Restricting Epithelial Stem/Progenitor Cell Activation and Expansion Stem Cells · 2006 · 176 citations
    21. Cell-Type-Specific Chromatin States Differentially Prime Squamous Cell Carcinoma Tumor-Initiating Cells for Epithelial to Mesenchymal Transition Cell stem cell · 2016 · 174 citations
    22. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012 · 170 citations
    23. Corneal Limbal Microenvironment Can Induce Transdifferentiation of Hair Follicle Stem Cells into Corneal Epithelial-like Cells Stem Cells · 2008 · 162 citations
    24. Wnt signaling induces epithelial differentiation during cutaneous wound healing BMC Cell Biology · 2006 · 159 citations
    25. Epithelial stem cells and implications for wound repair Seminars in Cell & Developmental Biology · 2012 · 156 citations
    26. The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014 · 149 citations
    27. Epithelial‐to‐mesenchymal transition in cutaneous wound healing: Where we are and where we are heading Developmental Dynamics · 2017 · 141 citations
    28. Epithelial Integrity Is Maintained by a Matriptase-Dependent Proteolytic Pathway ˜The œAmerican journal of pathology · 2009 · 137 citations
    29. Stem Cell Heterogeneity and Plasticity in Epithelia Cell Stem Cell · 2015 · 129 citations
    30. Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues Differentiation · 1988 · 124 citations