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    Glossary Epidermal Stem Cells

    specialized cells in the skin that regenerate and repair tissue

    Epidermal Stem Cells, also known as Skin Stem Cells, are specialized cells found in the outermost layer of the skin, the epidermis. These cells have the unique ability to self-renew and differentiate into various cell types that make up the epidermis, playing a crucial role in skin regeneration, wound healing, and maintaining the skin's barrier function.

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    Research 30 of 1000+

    1. Highly Upregulated Lhx2 in the Foxn1−/− Nude Mouse Phenotype Reflects a Dysregulated and Expanded Epidermal Stem Cell Niche PloS one · 2013 · 6 citations
    2. A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis Cell stem cell · 2021
    3. Effect of Flightless I Expression on Epidermal Stem Cell Niche During Wound Repair Advances in Wound Care · 2019 · 10 citations
    4. The arrector pili muscle, the bridge between the follicular stem cell niche and the interfollicular epidermis Anatomical Science International · 2016 · 14 citations
    5. Analysis on the maintenance mechanisms of human interfollicular epidermal stem cell and their niche Journal of dermatological science · 2016
    6. The stem cell niche The Journal of Pathology · 2008 · 209 citations
    7. Protective Mechanism of Adipose-Derived Stem Cells in Remodelling of the Skin Stem Cell Niche During Photoaging Cellular Physiology and Biochemistry · 2018 · 13 citations
    8. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    9. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011 · 396 citations
    10. Extracellular Matrix as a Regulator of Epidermal Stem Cell Fate International Journal of Molecular Sciences · 2018 · 57 citations
    11. Dormancy in the stem cell niche Stem Cell Research & Therapy · 2012 · 29 citations
    12. What does the concept of the stem cell niche really mean today? BMC biology · 2012 · 163 citations
    13. The Epithelial Stem Cell Niche in Skin Elsevier eBooks · 2017 · 9 citations
    14. TCF/Lef1 activity controls establishment of diverse stem and progenitor cell compartments in mouse epidermis The EMBO Journal · 2011 · 91 citations
    15. Decision letter: Hair follicle epidermal stem cells define a niche for tactile sensation 2018
    16. Collagen XVIIα1 in skin and hair aging: Mechanisms, stem cell niche regulation, and translational strategies Journal of Dermatological Science · 2026
    17. Cell death as an architect of adult skin stem cell niches Cell death and differentiation · 2024
    18. Targeting the stem cell niche: role of collagen XVII in skin aging and wound repair Theranostics · 2022 · 9 citations
    19. Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche Nature Reviews Molecular Cell Biology · 2013 · 133 citations
    20. Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth EMBO journal · 2018 · 34 citations
    21. Micropatterned dermal–epidermal regeneration matrices create functional niches that enhance epidermal morphogenesis Acta Biomaterialia · 2013 · 65 citations
    22. PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells Stem cell reports · 2017 · 22 citations
    23. Epidermal keratinocyte stem cells: their maintenance and regulation Seminars in cell biology · 1992 · 25 citations
    24. Somatic stem cell heterogeneity: diversity in the blood, skin and intestinal stem cell compartments Nature Reviews Molecular Cell Biology · 2015 · 137 citations
    25. Development and Maintenance of Epidermal Stem Cells in Skin Adnexa International journal of molecular sciences · 2020 · 15 citations
    26. Epidermal Cells Expressing Putative Cell Markers in Nonglabrous Skin Existing in Direct Proximity with the Distal End of the Arrector Pili Muscle Stem Cells International · 2016 · 5 citations
    27. Stem Cell Heterogeneity and Plasticity in Epithelia Cell Stem Cell · 2015 · 129 citations
    28. Biochemistry of epidermal stem cells Biochimica et Biophysica Acta (BBA) - General Subjects · 2012 · 26 citations
    29. 320 Desmoglein 3-mediated mechanical transadhesion controls epithelial stem cell quiescence 2021
    30. Skin Stem Cells, Their Niche and Tissue Engineering Approach for Skin Regeneration Advances in experimental medicine and biology · 2019 · 14 citations