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The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Retinoids increase steroid sulfatase activity in leukemia cells through RARα/RXR and involves certain pathways like phosphoinositide 3-kinase and ERK-MAP kinase.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

Metabolites and diet affect hair growth cycles in cashmere goats.

Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Finasteride may cause kidney damage.

PGD2 stops hair growth and is higher in bald men with AGA.

Essential oils may improve dogs' health and melatonin can help with their sleep and anxiety, but both should be used carefully.

Melasma's causes include genetics, sun exposure, hormones, and oxidative stress, and understanding these can help create better treatments.

Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.

Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Glutamine metabolism affects hair stem cell maintenance and their ability to change back to stem cells.

Human hair follicles can make and process prostaglandins, which may affect hair growth.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

CBD may improve skin and hair health, but its effective use and safety need more research.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Certain nutrients can help keep skin healthy as we age.

Some nutrients and antioxidants may improve skin and hair health, but more research is needed to confirm these benefits.