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Removing part of the vitamin D receptor stops vitamin D from working properly.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Nerves are crucial for the regeneration of various body parts in many animals.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The ZIP7 gene helps control zinc levels in cells by moving zinc from the Golgi apparatus to the cytoplasm.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

CDP is crucial for lung and hair follicle cell development.

Stem cell niches support, regulate, and coordinate stem cell functions.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Minoxidil can help grow hair in mice by making cells grow and improving hair quality. More research needed.

No effective treatment for frontal fibrosing alopecia was found, but oral 5-alpha-reductase inhibitors had the best response; for lichen planopilaris, topical corticosteroids were commonly used but had a high relapse rate.

The conclusion is that the increasing use of drugs for lifestyle reasons is a complex issue influenced by corporate profit, consumer behavior, and the medicalization of everyday life, with potential negative effects on personal well-being.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

TCDD speeds up skin barrier formation by increasing certain gene expressions.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

The conclusion is that tissue structure is key for stem cell communication and maintaining healthy tissues.

Follistatin helps hair growth and cycling, while activin prevents it.

The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.

The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.

Antioxidants may help fight oxidative stress linked to autoimmune skin diseases.

Dermoscopy helps diagnose and monitor treatment for hair loss from scarring conditions like discoid lupus and lichen planopilaris.