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    Glossary Dermal Papilla-Like Cells

    lab-grown cells mimicking natural dermal papilla cells for hair growth

    Dermal Papilla-Like Cells (DPLCs) are lab-grown cells that mimic the properties and functions of natural dermal papilla cells, which are found at the base of hair follicles and play a crucial role in hair growth and regeneration. These cells are often used in research and therapeutic applications to study hair loss conditions like alopecia and to develop potential treatments for promoting hair regrowth.

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    1. Trajectory of hiPSCs derived neural progenitor cells differentiation into dermal papilla-like cells and their characteristics Scientific reports · 2023
    2. Hair multiplication with dermal papilla like tissue containing human dermal papilla cells Biotechnology and Bioprocess Engineering · 2014
    3. Dermal Papilla Cells Improve the Wound Healing Process and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells Stem Cells Translational Medicine · 2014 · 68 citations
    4. Optimization of the reconstruction of dermal papilla like tissues employing umbilical cord mesenchymal stem cells Biotechnology and bioprocess engineering · 2010 · 6 citations
    5. Androgen Induction of Follicular Epithelial Cell Growth Is Mediated via Insulin-like Growth Factor-I from Dermal Papilla Cells Biochemical and biophysical research communications · 1995 · 173 citations
    6. Multipotent Neural Crest Stem Cell-Like Cells from Rat Vibrissa Dermal Papilla Induce Neuronal Differentiation of PC12 Cells BioMed research international · 2014 · 10 citations
    7. Hair growth promoting effect of dermal papilla like tissues from canine adipose-derived mesenchymal stem cells through vascular endothelial growth factor Journal of Veterinary Medical Science · 2016 · 8 citations
    8. Hair Growth Promoting Effect of Dermal Papilla Like Tissues from Canine Adipose-Derived Mesenchymal Stem Cells in Athymic Nude Mice 2016
    9. Regulation of human dermal papilla cell production of insulin-like growth factor binding protein-3 by retinoic acid, glucocorticoids, and insulin-like growth factor-1 Journal of cellular physiology · 1996 · 37 citations
    10. l-Ascorbic acid 2-phosphate promotes elongation of hair shafts via the secretion of insulin-like growth factor-1 from dermal papilla cells through phosphatidylinositol 3-kinase 2009 · 34 citations
    11. Induction of insulin‐like growth factor‐I by cepharanthine from dermal papilla cells: A novel potential pathway for hair growth stimulation The Journal of Dermatology · 2013 · 13 citations
    12. Extracellular vesicles from 3D cultured dermal papilla cells improve wound healing via Krüppel-like factor 4/vascular endothelial growth factor A -driven angiogenesis Burns and trauma · 2023 · 1 citations
    13. Secreted Frizzled‐Related Protein 2 ( SFRP2 ) Induces Follistatin‐Like 1 ( FSTL1 ) to Regulate Dihydrotestosterone ( DHT )‐Induced Dermal Papilla Cell Mitochondrial Dysfunction and Senescence Aging Cell · 2026
    14. Erythropoietin induces insulin-like growth factor-1 from three-dimensional culture of human dermal papilla cells Journal of Dermatological Science · 2012
    15. Direct reprogramming of human fibroblasts into hair-inducing dermal papilla cell-like cells by a single small molecule Biochemical Pharmacology · 2025
    16. Mycophenolate Antagonizes IFN-γ-Induced Catagen-Like Changes via β-Catenin Activation in Human Dermal Papilla Cells and Hair Follicles International Journal of Molecular Sciences · 2014 · 11 citations
    17. Chemically induced transformation of human dermal fibroblasts to hair‐inducing dermal papilla‐like cells Cell Proliferation · 2019 · 8 citations
    18. Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration Applied Materials Today · 2020 · 4 citations
    19. Glycyrrhizic acid attenuates stem cell-like phenotypes of human dermal papilla cells Phytomedicine · 2015 · 21 citations
    20. Exploration of <i>Aloe vera</i>, <i>Centella asiatica</i>, Green Tea, and <i>Pueraria mirifica</i> Extracts in Modulating Stem Cell-Like Properties for Hair Rejuvenation Through β-Catenin Stabilization and Activation of the Akt Signaling Cascade in Human Dermal Papilla Cells Natural Product Communications · 2025
    21. Direct Conversion of Human Fibroblasts into Hair-Inducing Dermal Papilla Cell-Like Cells by a Single Small Molecule SSRN Electronic Journal · 2024
    22. effects Of Low-level Laser Therapy (lllt) On Dermal Papilla Cell Proliferation And Insulin-like Growth Factor-1 (igf-1) Secretion From Balding Hair Follicles : #lb12 2014
    23. Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma Cell and tissue biology · 2009 · 7 citations
    24. Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells FEBS Open Bio · 2026
    25. Induction of hair follicle dermal papilla cell properties in human induced pluripotent stem cell-derived multipotent LNGFR(+)THY-1(+) mesenchymal cells Scientific Reports · 2017 · 42 citations
    26. Canine Adipose-Derived Stem Cell Aggregates as a Viable Substitute to Actual Canine Dermal Papillae Macedonian Veterinary Review · 2015 · 4 citations
    27. The chemotactic effect of a dermal papilla cell-derived factor on outer root sheath cells Journal of Dermatological Science · 2001 · 47 citations
    28. Rescuing key native traits in cultured dermal papilla cells for human hair regeneration Journal of Advanced Research · 2020 · 30 citations
    29. Effect of ethanol extract of plant mixture on hair regeneration in human dermal papilla cells and C57BL/6J mice Journal of Medicinal Plants Research · 2015 · 4 citations
    30. Low-frequency electromagnetic fields promote hair follicles regeneration by injection a mixture of epidermal stem cells and dermal papilla cells Electromagnetic Biology and Medicine · 2020 · 2 citations