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    Glossary Dermal Papilla Fibroblasts

    specialized cells at hair follicle base aiding hair growth

    Dermal Papilla Fibroblasts are specialized cells located at the base of hair follicles. They play a crucial role in hair growth and regeneration by interacting with other cells to regulate the hair cycle and provide essential signals for hair follicle development.

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    1. 613 Assessment of the induction and morphogenic potential of human hair matrix cells and dermal papilla fibroblasts ex vivo Journal of Investigative Dermatology · 2019 · 1 citations
    2. Engineering Spatially Organized Hair Peg-like Structures in Human Skin Constructs Using Keratinocyte–Dermal Papilla Fibroblast Spheroids and Micropatterned Dermal Scaffolds Acta Biomaterialia · 2026
    3. 773 Generation of human hair follicle organoids in vitro and ex vivo by co-culture of primary human hair matrix keratinocytes and dermal papilla fibroblasts Journal of Investigative Dermatology · 2020
    4. Hair Strengthening Evaluation of Anisotropic Osmolite Solutions (Inositol + Arginine): Cross-Talk between Dermal Papilla Fibroblast and Keratinocytes of the Outer Root Sheath Using a µHair Follicle 3D Model Cosmetics · 2018
    5. Keratinocytes maintain compartmentalization between dermal papilla and fibroblasts in 3D heterotypic tri‐cultures Cell Proliferation · 2019 · 16 citations
    6. Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts Archives of Dermatological Research · 2005 · 9 citations
    7. Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells 2007 · 66 citations
    8. Extracellular Vesicles from Activated Dermal Fibroblasts Stimulate Hair Follicle Growth Through Dermal Papilla-Secreted Norrin Stem cells · 2019 · 37 citations
    9. Chemically induced transformation of human dermal fibroblasts to hair‐inducing dermal papilla‐like cells Cell Proliferation · 2019 · 8 citations
    10. Effect of Fibroblast Growth Factor 10 and an Interacting Non-Coding RNA on Secondary Hair Follicle Dermal Papilla Cells in Cashmere Goats’ Follicle Development Assessed by Whole-Transcriptome Sequencing Technology Animals · 2023 · 2 citations
    11. Expression Profiles of Tyrosine Kinases in Cultured Follicular Papilla Cells Versus Dermal Fibroblasts Journal of Investigative Dermatology · 2004 · 11 citations
    12. Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration Applied Materials Today · 2020 · 4 citations
    13. Primary cell culture and morphological characterization of canine dermal papilla cells and dermal fibroblasts Veterinary Dermatology · 2002 · 32 citations
    14. Engineered Nanovesicles from Fibroblasts Modulate Dermal Papillae Cells In Vitro and Promote Human Hair Follicle Growth Ex Vivo Cells · 2022 · 4 citations
    15. Effect of Marine-Derived Saccharides on Human Skin Fibroblasts and Dermal Papilla Cells Marine Drugs · 2023 · 2 citations
    16. Hair-follicle dermal papilla and sheath fibroblasts provide a supportive microenvironment for human skin regeneration 2017 · 3 citations
    17. Human hair follicle dermal papilla cell, dermal sheath cell and interstitial dermal fibroblast characteristics. PubMed · 1996 · 36 citations
    18. Direct Reprograming of Mouse Fibroblasts into Dermal Papilla Cells via Small Molecules International Journal of Molecular Sciences · 2022 · 3 citations
    19. Direct reprogramming of human fibroblasts into hair-inducing dermal papilla cell-like cells by a single small molecule Biochemical Pharmacology · 2025
    20. Fibroblast growth factor 5-short (FGF5s) inhibits the activity of FGF5 in primary and secondary hair follicle dermal papilla cells of cashmere goats Gene · 2015 · 42 citations
    21. Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles International Journal of Molecular Medicine · 2011 · 28 citations
    22. Comparative secretome analysis of human follicular dermal papilla cells and fibroblasts using shotgun proteomics BMB Reports · 2012 · 44 citations
    23. Strengthening the cellular function of dermal fibroblasts and dermal papilla cells using nanovesicles extracted from stem cells using blue light-based photobiomodulation technology Biomaterials Science · 2025 · 3 citations
    24. Soluble factors from human hair papilla cells and dermal fibroblasts dramatically increase the clonal growth of outer root sheath cells Archives of Dermatological Research · 1993 · 62 citations
    25. Direct Conversion of Human Fibroblasts into Hair-Inducing Dermal Papilla Cell-Like Cells by a Single Small Molecule SSRN Electronic Journal · 2024
    26. 1429 Proteomic analysis of cultured dermal papilla, dermal sheath and dermal fibroblast cells from female scalp highlights alterations in the cell populations with increasing age Journal of Investigative Dermatology · 2023
    27. Corrections to “Adenosine Stimulates Fibroblast Growth Factor-7 Gene Expression Via Adenosine A2b Receptor Signaling in Dermal Papilla Cells” Journal of Investigative Dermatology · 2007
    28. Differentiation capacity of stromal fibroblast-like cells from human bone marrow, adipose tissue, hair follicle dermal papilla and derma Cell and tissue biology · 2009 · 7 citations
    29. Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells Cell and Tissue Research · 2013 · 28 citations
    30. 564 Subpopulations of dermal fibroblasts produce distinct extracellular matrices 2016