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    Glossary Cyclin D1

    regulates cell cycle progression from G1 to S phase

    Cyclin D1, also known as CCND1, is a protein that plays a crucial role in regulating the cell cycle, specifically the transition from the G1 phase to the S phase, where DNA replication occurs. It acts as a regulatory subunit for certain enzymes called cyclin-dependent kinases (CDKs), and its overexpression is often associated with various types of cancer, as it can lead to uncontrolled cell proliferation.

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    1. Epidermal Growth Factor Induces Proliferation of Hair Follicle-Derived Mesenchymal Stem Cells Through Epidermal Growth Factor Receptor-Mediated Activation of ERK and AKT Signaling Pathways Associated with Upregulation of Cyclin D1 and Downregulation of p16 Stem Cells and Development · 2016 · 83 citations
    2. RhoA promotes epidermal stem cell proliferation via PKN1-cyclin D1 signaling PLoS ONE · 2017 · 21 citations
    3. Circ-Smad5 retards the G1/S transition of cell cycle via inhibiting the activity of wnt/lef/cyclind1 signaling in JB6 cells Genes & Diseases · 2020 · 10 citations
    4. Does D matter? The role of vitamin D in hair disorders and hair follicle cycling Dermatology Online Journal · 2010 · 98 citations
    5. Cyclin D3 deficiency inhibits skin tumor development, but does not affect normal keratinocyte proliferation Oncology Letters · 2017 · 2 citations
    6. Vitamin D and the skin: Focus on a complex relationship: A review Journal of Advanced Research · 2014 · 139 citations
    7. Novel mechanisms for the vitamin D receptor (VDR) in the skin and in skin cancer The Journal of Steroid Biochemistry and Molecular Biology · 2014 · 71 citations
    8. The Transient Role for Calcium and Vitamin D during the Developmental Hair Follicle Cycle Journal of Investigative Dermatology · 2016 · 18 citations
    9. Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours Development · 2002 · 297 citations
    10. Patched1 Functions as a Gatekeeper by Promoting Cell Cycle Progression Cancer Research · 2006 · 176 citations
    11. Deregulated expression of E2F1 induces hyperplasia and cooperates with ras in skin tumor development Oncogene · 1998 · 136 citations
    12. 1α,25(OH)2-Dihydroxyvitamin D3/VDR protects the skin from UVB-induced tumor formation by interacting with the β-catenin pathway The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    13. Combination of herbal extracts and platelet-rich plasma induced dermal papilla cell proliferation: involvement of ERK and Akt pathways Journal of Cosmetic Dermatology · 2013 · 39 citations
    14. Induction of Hair Growth by Insulin-Like Growth Factor-1 in 1,763 MHz Radiofrequency-Irradiated Hair Follicle Cells PLoS ONE · 2011 · 39 citations
    15. Pre‐clinical evidences for the efficacy of tryptanthrin as a potent suppressor of skin cancer Cell Proliferation · 2019 · 36 citations
    16. A role of placental growth factor in hair growth Journal of dermatological science · 2014 · 31 citations
    17. Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100 Journal of nanobiotechnology · 2021 · 29 citations
    18. Effects of glucocorticoid on human dermal papilla cells in vitro The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 27 citations
    19. Allopregnanolone promotes proliferation and differential gene expression in human glioblastoma cells Steroids · 2017 · 25 citations
    20. Herbal Extracts Induce Dermal Papilla Cell Proliferation of Human Hair Follicles Annals of Dermatology · 2015 · 24 citations
    21. Activin B Stimulates Mouse Vibrissae Growth and Regulates Cell Proliferation and Cell Cycle Progression of Hair Matrix Cells through ERK Signaling International Journal of Molecular Sciences · 2019 · 23 citations
    22. Costunolide promotes the proliferation of human hair follicle dermal papilla cells and induces hair growth in C57BL/6 mice Journal of Cosmetic Dermatology · 2018 · 21 citations
    23. Effects of dihydrotestosterone on rat dermal papilla cells in vitro European Journal of Pharmacology · 2015 · 19 citations
    24. Promotion effect of acankoreoside J, a lupane-triterpene in Acanthopanax koreanum, on hair growth Archives of Pharmacal Research · 2012 · 17 citations
    25. Vanillic Acid Stimulates Anagen Signaling via the PI3K/Akt/ β-Catenin Pathway in Dermal Papilla Cells Biomolecules & Therapeutics · 2020 · 14 citations
    26. Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways Frontiers in pharmacology · 2018 · 14 citations
    27. Twist1 Contributes to the Maintenance of Some Biological Properties of Dermal Papilla Cells in vitro by Forming a Complex With Tcf4 and β-Catenin Frontiers in Cell and Developmental Biology · 2020 · 13 citations
    28. Regulatory effect of β-catenin on proliferation of hair follicle stem cells involves PI3K/Akt pathway Journal of Applied Biomedicine · 2013 · 11 citations
    29. Assessment of the anti‐hair loss potential of <i>Camellia japonica</i> fruit shell extract in vitro International Journal of Cosmetic Science · 2022 · 10 citations
    30. Cell Density-Dependent Upregulation of PDCD4 in Keratinocytes and Its Implications for Epidermal Homeostasis and Repair International Journal of Molecular Sciences · 2015 · 10 citations