Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study aims to determine if an integrated early childhood development package can reduce developmental delays among two-year-old children in public health centers in Pakistan.

This study reports that sacituzumab govitecan achieved a 33.3% overall response rate in patients with metastatic triple-negative breast cancer who had prior treatments, with a median response duration of 7.7 months.

This study found that inhibiting the interaction between HOTAIR and EZH2 can block pro-fibrotic gene expression in fibroblasts and interfere with tissue remodeling in systemic sclerosis patient skin.

This report describes early and late stages of central centrifugal cicatricial alopecia in two Black women, highlighting progression from a small to a large central patch of hair loss.

This study characterized the SARM PF-05314882, finding it demonstrates anabolic activity in rats with minimal effects on the prostate, seminal vesicles, and luteinizing hormone levels.

This review observed limited evidence of clinically significant benefits from treatments for acute central serous chorioretinopathy, which often resolves spontaneously, but identified PDT and micropulse laser as the most promising for further trials.

This case report describes a 3-year-old boy with trichothiodystrophy, highlighting specific MRI findings of diffuse dysmyelination and osteosclerosis that may be unique to the disorder.

This case report describes the first recorded instance of congenital triangular alopecia in the mid-frontal scalp region, challenging the assumption that it is restricted to the frontotemporal area.

This study found that skin organoids derived from iPSCs with an HS-associated NCSTN mutation showed defects in hair follicle stem cell differentiation and increased expression of inflammatory proteins related to hidradenitis suppurativa.

The authors report that a 62-year-old woman with invasive conjunctival squamous cell carcinoma experienced complete remission two years after combining cemiplimab, retinoic acid, and IFNα-2b treatments, highlighting potential utility despite limited availability of IFNα-2b.

This study found that women with common baldness treated with cyclical antiandrogen therapy for 52 weeks experienced increased hair density and a higher percentage of hairs in the anagen growth phase.

This pilot study found that night shift workers showed fewer signs of wrinkle formation compared to day workers, but there were no significant differences in DNA amplification or collagen percentage.

In this study, extracorporeal shock wave treatment for female pattern hair loss resulted in significant increases in hair count and thickness in 20 women, with 85% of participants perceiving improvements in hair volume.

This study examines how conditions like PSSD, Long COVID, and ME/CFS form a "Post-Exposure Syndromes" family, initiated by transient exposures but persisting due to complex state-space dynamics, and suggests improving pharmacovigilance to better address and understand these persistent syndromes.

This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.

A 5-year-old boy was diagnosed with congenital triangular alopecia, a type of hair loss without skin changes, usually starting between ages 2-5, with no specific treatment.

This article discusses revised SLE classification criteria by the SLICC and reports no new research results.

This study reports a unique case of trichotillomania as a presenting sign in a patient with neurological Wilson's disease, confirmed by genetic testing and copper abnormalities.

This study used whole-genome sequence data to identify numerous putative causal variants and genes affecting key wool traits and skin wrinkle in Merino sheep, highlighting their polygenic and pleiotropic nature.

This case study presented by the researchers describes the effective use of topical calcipotriene ointment in treating a 6-year-old girl with en coup de sabre scleroderma, resulting in normalization of the sclerotic skin, hair regrowth, and improved pigmentation.

This study found that ultraviolet light-enhanced visualization can detect subtle skin changes linked to carotene and vitamin A deficiency, which improved with dietary correction in deficient individuals.

This study reported that Trichoscan, a computer-assisted hair measurement system, was not supported as accurate for clinical trials due to errors in signal detection, despite its analysis speed.

This review discusses hair tourniquet syndrome, highlighting its potential for delayed diagnosis and the association with maternal telogen effluvium, but reports no new clinical results.

The drug TGU was ineffective against small cell lung cancer and caused significant bone marrow suppression.

This study found that human basal cell and squamous cell carcinomas have distinct gene expression patterns, with specific up-regulation of zinc finger encoding genes in basal cell carcinoma.

This review highlights the potential of Sacituzumab Tirumotecan, an antibody-drug conjugate, in treating gynecologic cancers, with ongoing Phase III trials indicating a manageable safety profile and future results expected to shed light on its effectiveness in improving survival and response rates.

This study found that teledermatology significantly reduced wait times and increased appointment availability for uninsured Latino immigrants, effectively triaging 70% of cases without in-person visits.

Trichoscopy helped diagnose and treat a child's fungal scalp infection by spotting specific hair shapes.

This study identified significant gene expression differences in human basal cell carcinoma, including up-regulation of zinc finger encoding genes, which are not entirely reflected in current mouse models.

This study analyzed the swelling behavior of human hair during permanent waving treatment, finding that both the microstructure and macrostructure of intermediate filaments swell simultaneously at the initial stage, and while partially destructed by reduction, they are considerably restored through oxidation.