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This study found that blocking corticotropin-releasing factor receptors with astressin-B promoted hair regrowth and prevented alopecia in a mouse model of stress-induced hair loss.

This study suggests that caribine may enhance the interaction between CRFR and maltose binding protein, potentially offering a new approach for treating hair loss.

This study established a stable cell line for CRF1 receptor screening, which can be used to develop functional cosmetics and modulators potentially affecting hair re-growth.

This study found that stress hormones, particularly CRF, can inhibit hair growth and induce hair loss by affecting human dermal papilla cells and hair follicles, suggesting a functional HPA axis in these cells.

This study found that corticotropin-releasing factor influences cytokine expression related to hair growth in human dermal papilla cells and suggests CRF receptor antagonists could be potential treatments for stress-induced hair loss.

This study reviewed the current understanding of congenital adrenal hyperplasia from 21-hydroxylase deficiency, highlighting the impact of universal newborn screening in reducing mortality and discussing ongoing treatment challenges and future therapeutic prospects.

In this study, socially defeated mice showed increased alcohol consumption, and CRF-R1 antagonism selectively reduced drinking in these mice, suggesting a potential treatment target for stress-related alcohol use disorders.

This review discusses the use of antiandrogens like flutamide and its derivatives in prostate cancer treatment and highlights the need for next-generation antiandrogens for improved efficacy; it reports no new clinical results.

This study found that premature hair loss due to stress does not occur in NK-1 receptor knockout or mast cell deficient mice, suggesting a key role for neurokinin substance P and mast cell interaction in stress-related hair follicle changes.

This study found that serum androgen levels in premenopausal women may be influenced by genetic variants of the androgen receptor and estrogen receptor β genes.

This study found that tildacerfont treatment in males with congenital adrenal hyperplasia reduced androgen levels and improved markers of testicular function, suggesting potential benefits for male reproductive health.

This study found that foot shock stress prolonged the telogen stage and delayed anagen induction in the hair cycle of non-depilated mice, potentially through stress-induced actions of substance P.

This study provides evidence that psychoemotional stress inhibits hair growth in mice by affecting the brain-hair follicle axis, with specific neuropeptides and treatments modulating this effect.

This review discusses sex differences in the neuroendocrine response to stress, focusing primarily on rodent studies, and highlights open questions about the roles of gonadal hormones and sex chromosomes.

This review discusses Chrousos syndrome, a rare condition caused by NR 3C1 gene mutations leading to glucocorticoid resistance, and reports no new clinical results; early identification and genetic testing are recommended for diagnosis.

This study suggests that chronic stress can lead to decreased skin pigmentation in mice by disrupting the skin's HPA axis, potentially making stress a risk factor for depigmentation.

This review discusses how neuroendocrine pathways influence keratin regulation in human skin and hair follicles and suggests these pathways as potential targets for new treatments of skin disorders, but reports no clinical results.

This review discusses how neurosteroids acting on GABAA receptors may influence behavior and explores the potential for developing selective modulators for treating psychiatric disorders, but reports no new clinical results.

This study found that chronic stress may inhibit hair follicle growth and melanogenesis in mice through modulation of the central HPA axis, with C57BL/6 mice appearing most sensitive to these effects.

In this study, the authors found that applying hypobaric pressure to the skin significantly increases the transdermal permeation of large molecules by enhancing diffusion, despite the associated skin stretching and hair follicle enlargement not fully explaining this effect.

This study found that neonatal blocking of androgen and estrogen pathways in rats altered sex-specific expression of estrogen and androgen receptors in adult pituitary and adrenal glands, potentially influencing lifelong neuroendocrine function.

This review discusses recent advancements in understanding neuroendocrine regulation of keratin biology and highlights the potential of neurohormones to treat skin disorders, but it reports no new clinical results.

Stress may affect hair growth by influencing hair follicle development and could contribute to hair loss.

This review discusses the role of various hormones in diffuse hair loss and emphasizes the need for further research to clarify their complex interactions and potential therapeutic implications, but reports no new clinical results.

This study observed that acute stress in rats increased neurosteroid levels linked to enhanced GABA(A) receptor function, raising seizure thresholds, while similar effects were seen in mice with deoxycorticosterone administration.

This study demonstrated that water-soluble peptides from egg yolk, termed "hair growth peptide," stimulated human hair follicle cell growth and improved hair growth in female pattern hair loss.

This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.

This study found that progesterone and its metabolite, allopregnanolone, provided anti-anxiety and anti-depressive effects in female mice, potentially independent of nuclear progestin receptors but requiring 5α-reduction and estradiol's influence on brain-derived neurotrophic factor.

This article discusses the potential of acupuncture as a complementary or alternative therapy for PCOS, highlighting experimental evidence of its positive effects on reproductive and metabolic function, but reports no new clinical results.