January 2024 in “Institutional Repositories DataBase (IRDB)” This study developed a method to measure local steroid hormone concentrations in hair, providing new insights into hormone dynamics associated with androgenetic alopecia.
July 1998 in “Chromatographia” Women with effluvium have higher levels of certain urinary steroids, possibly due to stress and increased adrenal activity.
January 2012 in “CINECA IRIS Institutial Research Information System (University of Genoa)” This study observed fluctuations in hair cortisol levels in rabbits, indicating their HPA axis activity responded similarly to surgical and environmental stressors, suggesting potential anthropomorphic evaluations of stress.
237 citations
,
September 2018 in “Clinical Biochemistry” Hair cortisol analysis can help diagnose stress-related conditions but needs more refinement for widespread use.
199 citations
,
July 2007 in “General and Comparative Endocrinology” In this study, researchers found a significant positive association between cortisol levels in hair and feces of domestic cats and dogs, suggesting hair cortisol assays could be a viable option for monitoring chronic stress.
57 citations
,
February 1983 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” This study found that pubic skin fibroblasts respond to androgens, increasing 5α-reductase activity via an androgen receptor-mediated mechanism, suggesting its potential as a marker of androgen action in vitro.
16 citations
,
March 2013 in “Clinica Chimica Acta” Cortisol and cortisone release from hair increases in steps over time during incubation.
12 citations
,
December 2017 in “Scientific reports” This study reported that pulverizing hair samples significantly improves the precision of testosterone measurement, with higher testosterone concentrations observed in men than in women.
November 2025 in “Contraception” This study suggests that using combined oral contraceptives does not increase hair glucocorticoid levels, but hair treatments should be considered as a confounder in stress biomarker assessments.
March 2022 in “VNU Journal of Science Medical and Pharmaceutical Sciences” This study developed a sensitive method using LC-ESI-MS/MS for accurate and reliable measurement of nine steroid hormones in children's serum.
April 2025 in “Medical Journal of Babylon” This study found that male patients with alopecia areata had significantly higher levels of copeptin and cortisol compared to healthy controls, suggesting these biomarkers could play a role in the condition's pathophysiology and may serve as diagnostic indicators.
33 citations
,
January 2017 in “Conservation physiology” This study found that measuring reproductive hormone levels in brown bear hair may effectively support non-invasive genetic sampling, though larger samples or more sensitive techniques are needed for broader application.
21 citations
,
January 2020 in “Conservation Physiology” This study found that cortisol concentrations were significantly higher in hair samples with follicles compared to those without, suggesting potential confounding in stress assessments using different hair sampling methods.
19 citations
,
June 2020 in “General and comparative endocrinology” This study found that hair cortisol concentration is a promising stress indicator in cattle but not in pigs, where external factors and lower cortisol response may interfere with its validity.
5 citations
,
January 2021 in “PeerJ” This study observed that high levels of immunoreactive cortisol in the tail hair of captive Asian elephants were often associated with stressful or distinct behavioral events, suggesting its potential for reconstructing their physiological history.
90 citations
,
July 2014 in “Conservation Physiology” This study found that hair cortisol concentration in free-ranging brown bears is influenced by handling methods, body condition, and potentially both short- and long-term stressors.
76 citations
,
October 2011 in “Clinica Chimica Acta” In this study, ultraviolet irradiation and immersion in shampoo and hot water significantly reduced hair cortisol, illustrating a two-stage process of cortisol loss that may impact chronic stress assessment.
49 citations
,
April 2016 in “International journal of molecular sciences” This study found that shift nurses exhibited lower circadian variations compared to daytime nurses, indicating an adjustment of their biological clocks to continuous shift schedules.
46 citations
,
August 1990 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, ketoconazole treatment improved acne in all women and reduced hirsutism in some, but it caused several side effects and requires careful monitoring.
24 citations
,
April 2008 in “Fertility and sterility” In this study, pioglitazone treatment in insulin-resistant PCOS patients decreased relative 5alpha-reductase activity without significantly affecting cortisol levels or urinary cortisol excretion.
16 citations
,
March 2000 in “Clinical Biochemistry” In this study, women with androgenic alopecia showed increased excretion of steroid metabolites and heightened 5α-reductase activity, suggesting these may contribute to the condition's hormonal abnormalities.
12 citations
,
December 2020 in “Comprehensive psychoneuroendocrinology” This study found that progesterone levels were higher and increased significantly throughout pregnancy, contrasting with stable levels in non-pregnant women.
10 citations
,
May 2018 in “Forensic Science International” This study concluded that the process of mummification disfigures facial features, making identification challenging, but commercial shrunken heads retain more defining features compared to ceremonial ones.
7 citations
,
October 2015 in “American Journal of Primatology” The researchers observed that pregnancy in rhesus monkeys was associated with an increased incidence of hair loss, though the underlying reasons remain unclear.
October 2025 in “Journal of Veterinary Diagnostic Investigation” This study found that in domestic cats, black hair contained significantly higher cortisol concentrations than white hair, whereas ginger hair showed no significant difference compared to white hair. Additionally, a positive correlation was reported between hair cortisol levels and behavioral issues mentioned by cat owners.
This study is designed to explore how circadian rhythms are affected by obesity and mental health conditions, such as schizophrenia and bipolar disorder, using biological and lifestyle data from independently living adults.
June 2020 in “Authorea (Authorea)” This study observed that pregnant women experienced an increase in hair cortisol concentrations, with primiparae having significantly higher levels in the last trimester compared to multiparae.
This study reports that hair samples can be used to track chronic hormone levels, revealing stress, reproductive, and sodium regulation patterns in wildebeest related to environmental factors.
January 2017 in “Qucosa (Saxon State and University Library Dresden)” This study found that plasma protein binding significantly contributes to the shifts in glucocorticosteroid concentration ratios among blood, saliva, and hair, challenging prior assumptions about enzyme inactivation as the main factor.
October 2023 in “Animal production science” This study investigated how vitamin A deficiency, certain diseases, and pregnancy affect cattle coat hair structure, finding notable keratin fibril interference under vitamin A deficiency and structural modifications in chronic renal failure, while pregnant cows exhibited superior hair tensile strength compared to non-pregnant ones.