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This review explores the potential of metal nanoparticles as innovative treatments for alopecia, highlighting their effectiveness in promoting hair regrowth, enhancing drug delivery, and modulating gene expression while also assessing the related experimental methodologies and regulatory considerations.

This study found that subcutaneous injections of certain chelators led to skin and hair depigmentation, increased skin elasticity, and disturbed hair growth in minks, without affecting fur quality.

This study reports a unique case of trichotillomania as a presenting sign in a patient with neurological Wilson's disease, confirmed by genetic testing and copper abnormalities.

This study demonstrated that using chelants like N , N ′ ‐ethylenediamine disuccinic acid in hair coloring products can significantly reduce keratin fiber damage by preventing the formation of metal-induced free radicals.

This letter discusses the various risk factors associated with premature greying of hair, highlighting genetic predispositions, nutritional deficiencies, stress, and lifestyle factors, while noting a lack of conclusive data on effective interventions, as detailed in the reviewed studies.

This study found no differences in trace element concentrations between Finnish alopecia patients and the normal population, but noted significant serum copper variation among different alopecia subtypes.

This article reviews inherited mineral and trace element disturbances and reports no clinical results; it highlights conditions like hypomagnesaemia and acrodermatitis enteropathica linked to impaired nutrient absorption.

This study found that an increased calcium/magnesium ratio in hair and lower chromium concentration were associated with higher insulin resistance in Korean adult males.

This study found that variations in mineral content of hair, such as increased Zr in asthma and respiratory infections, may be linked to different illnesses, suggesting potential diagnostic use.

This study found that mange was the most common cause of alopecia in dogs, with cases being more prevalent during the summer and among dogs less than one year old.

This study in Aswan governorate reported that emaciated cattle showed decreased blood cell counts and serum minerals, as well as elevated liver enzymes, possibly associated with parasitic infections.

In this study, Hibiscus rosa-sinesis flower extract was found to contain 0.33% quercetin according to HPTLC analysis and 0.37% according to HPLC. Heavy metals measured were within acceptable limits, supporting the standardization of the plant material for efficacy and safety testing.

This case report suggests that a supplement containing biotin, beta carotene, vitamin C, zinc, and copper may improve insulin resistance markers and hair loss in a patient with non-classic 11-hydroxylase deficiency.

This study analyzed hair samples from marathon runners with hair loss, finding distinct patterns in mineral content and heavy metal contamination, with more male than female runners experiencing hair loss.

In this study, researchers found that genetic and non-genetic factors, including deficiencies in micronutrients like zinc and vitamins, play varying roles in the development of androgenetic alopecia in men.

This review discusses various potential adverse effects of common oral vitamin and mineral supplements used in dermatology and highlights lesser-known issues like hematologic and neurologic effects from zinc.

In this study of sheep across various breeds and ages, researchers found that Trichophyton mentagrophytes caused severe dermatophytosis, especially affecting young Shahbadi sheep during winter, leading to notable anemia and skin lesions.

This study found that urinary selenium to creatinine ratio and serum selenium concentrations quickly respond to changes in dietary selenium, making them useful biomarkers for assessing selenium status in dogs.

This study found that hemodialysis patients taking water-soluble vitamins had a 16% lower mortality risk compared to those not taking any, but the specific supplementation needed remains unclear.

In this study conducted at the Veterinary Clinical Complex in Bikaner, Rajasthan, researchers found that among 240 canine dermatitis cases, 25 dogs had demodicosis, characterized by various hematological and serum biochemical changes, and distinctive histopathological alterations in skin samples.

This study developed a dissolvable microneedle system loaded with nanozymes and minoxidil that enhanced hair regeneration in androgenetic alopecia mouse models by improving blood flow, reducing reactive oxygen species, and increasing cell proliferation compared to minoxidil alone.

In AGA mouse models, this study found that the combination of nickel–copper nanozymes and minoxidil in dissolvable microneedles significantly enhanced hair regeneration and improved the hair follicle microenvironment by reducing reactive oxygen species and increasing vascular density, compared to minoxidil alone.

This narrative review describes the components of human hair and their nutritional importance but reports no clinical results; the authors suggest dietary sulfur amino acids are essential for hair health.

This study found that diabetic individuals had significantly lower hair levels of chromium, manganese, and copper, but higher iron levels, compared to non-diabetic controls.

This review discusses the association between hair element levels and autism spectrum disorder, reporting links between neurotoxic elements like mercury and lead and pathogenesis, alongside potentially protective roles for zinc and copper balance.

This study found significant reductions in zinc, copper, and iron levels in patients with idiopathic telogen effluvium compared to healthy controls, suggesting a potential role for trace element deficiency in the condition.

This study found that children with repetitive respiratory tract infections had significantly lower levels of the trace elements zinc, iron, and copper in their hair compared to healthy children.

This study found that urinary and serum selenium levels were the most sensitive biomarkers for selenium intake in adult dogs, with serum GPx responding more quickly than whole blood GPx.

This study suggests that hair analysis detecting trace elements like copper and iron may help in screening for diseases such as hepatocellular carcinoma and osteoporosis, due to altered element concentrations in patients.

In this study, Bushman women in various life stages had higher levels of iron and zinc in their hair compared to Bantu and American mothers, with iron deficiency anemia being rare among them.