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    Glossary Chronic Wounds

    injuries that don't heal within a typical 3-month period

    Chronic wounds, also known as non-healing or persistent wounds, are injuries to the skin that fail to progress through the normal stages of healing within a predictable timeframe, typically around 3 months. These wounds can result from various underlying conditions such as diabetes, poor circulation, or prolonged pressure, and often require specialized medical treatment to promote healing and prevent complications like infection.

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    Research 30 of 1000+

    1. Systematic Review: Adipose-Derived Mesenchymal Stem Cells, Platelet-Rich Plasma and Biomaterials as New Regenerative Strategies in Chronic Skin Wounds and Soft Tissue Defects International Journal of Molecular Sciences · 2021 · 70 citations
    2. A Concise Review on Tissue Engineered Artificial Skin Grafts for Chronic Wound Treatment: Can We Reconstruct Functional Skin Tissue In Vitro? Cells · 2020 · 133 citations
    3. In vivo expansion and regeneration of full‐thickness functional skin with an autologous homologous skin construct: Clinical proof of concept for chronic wound healing International Wound Journal · 2019 · 38 citations
    4. A Systematic Review of Spironolactone Nano-Formulations for Topical Treatment of Skin Hyperandrogenic Disorders and Chronic Wounds Pharmaceutics · 2024
    5. Toward understanding scarless skin wound healing and pathological scarring F1000Research · 2019 · 113 citations
    6. Engineering Immunomodulatory Biomaterials to Drive Skin Wounds toward Regenerative Healing Cold Spring Harbor Perspectives in Biology · 2022 · 18 citations
    7. Rothmund‐Thomson syndrome type 2 – a rare cause of chronic wounds Journal der Deutschen Dermatologischen Gesellschaft · 2019
    8. Ginseng-derived nanoparticles induce skin cell proliferation and promote wound healing Journal of Ginseng Research · 2022 · 112 citations
    9. Mechanistic Insights into Plant-Derived Exosomes, Their Cross-Kingdom Effects, and Potential Biomedical Applications in Skin Wounds Repair Plants · 2026
    10. Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications International journal of molecular sciences · 2015 · 232 citations
    11. Application and progress of induced pluripotent stem in chronic wound healing: a narrative review BMC Plastic and Reconstructive Surgery · 2026
    12. Development of novel wound dressing based on elastin-like recombinamers for skin regeneration 2024
    13. Cellular Heterogeneity and Plasticity of Skin Epithelial Cells in Wound Healing and Tumorigenesis Stem cell reviews and reports · 2022 · 7 citations
    14. Hydrogel-based neural engineering for skin wound healing Frontiers in Cell and Developmental Biology · 2026 · 1 citations
    15. Research advances on postbiotics in promoting skin wound healing: mechanisms, formulations, and clinical translation Frontiers in Immunology · 2026
    16. 577 Successful allogeneic epidermal grafting of chronic recessive dystrophic epidermolysis bullosa wounds from hematopoietic cell donors in the outpatient setting Journal of Investigative Dermatology · 2019
    17. Editorial: Inflammation, stem cells and wound healing in skin aging Frontiers in Cell and Developmental Biology · 2022
    18. Skin manifestations of chronic kidney disease Actas Dermo-Sifiliográficas · 2015 · 19 citations
    19. Adipose-derived stem cells applied in skin diseases, wound healing and skin defects: a review Cytotherapy · 2022 · 2 citations
    20. The Immune Functions of Keratinocytes in Skin Wound Healing International Journal of Molecular Sciences · 2020 · 147 citations
    21. Skin manifestations of chronic kidney disease Actas Dermo-Sifiliográficas · 2015
    22. A Comprehensive Review on Platelet-Rich Plasma Activation: A Key Player in Accelerating Skin Wound Healing Curēus · 2023 · 2 citations
    23. States and Fates of Skin Fibroblasts Revealed through Chromatin Accessibility Journal of Investigative Dermatology · 2022
    24. Advanced therapies of skin injuries Wiener Klinische Wochenschrift · 2015 · 28 citations
    25. Obesity and Wound Healing: Focus on Mesenchymal Stem Cells Life · 2023 · 3 citations
    26. Hair follicle-inspired therapies for wound healing and scar remodelling Journal of Plastic Reconstructive & Aesthetic Surgery · 2025 · 2 citations
    27. Recent advances and challenges in 3D bioprinting for skin tissue regeneration International Journal of Bioprinting · 2026
    28. Skin biology Elsevier eBooks · 2019 · 5 citations
    29. Human relevant platforms for cutaneous wound healing research: current landscape, translational gaps, and emerging frontiers Frontiers in Bioengineering and Biotechnology · 2026
    30. Myrtus communis Leaf Extract Modulates IL-1α and VEGF Gene Expressions in HaCaT Cells: Probable Implications for Its Beneficial Effects in Hair Loss and Wound Healing Clinical Cosmetic and Investigational Dermatology · 2026