Search
for

    Did you mean Planar Cell Polarity?
    Glossary Planar Cell Polarity

    coordinated orientation of cells within tissue plane

    Planar Cell Polarity (PCP) refers to the coordinated orientation of cells along a tissue plane, rather than just up and down. This is crucial for various biological processes, such as the uniform direction of hair growth on the skin or the proper alignment of cells in the inner ear for hearing.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Barley disease susceptibility factor RACB acts in epidermal cell polarity and positioning of the nucleus Journal of experimental botany · 2016 · 41 citations
    2. The Role of Cell Polarity Regulator aPKC in Hair Follicle Stem Cell Maintenance and Wound Healing Nihon Ika Daigaku Igakkai Zasshi · 2020
    3. Responses of hair follicle–associated structures to loss of planar cell polarity signaling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 29 citations
    4. Planar cell polarity effector gene Intu regulates cell fate-specific differentiation of keratinocytes through the primary cilia Cell death and differentiation · 2012 · 19 citations
    5. Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse Journal of Investigative Dermatology · 2009 · 92 citations
    6. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns Developmental Biology · 2017 · 33 citations
    7. Functional redundancy of <i>Frizzled 3</i> and <i>Frizzled 6</i> in planar cell polarity control of mouse hair follicles Development · 2018 · 24 citations
    8. Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity Frontiers in cell and developmental biology · 2023 · 7 citations
    9. 236 Wnt/planar cell polarity impairment and the genetics of yellow nail syndrome Journal of Investigative Dermatology · 2024
    10. A cell polarity protein, aPKCλ, is essential for maintaining hair follicle stem cell quiescence and hair follicle regeneration Journal of Dermatological Science · 2016
    11. Essential Role of Polarity Protein Par3 for Epidermal Homeostasis through Regulation of Barrier Function, Keratinocyte Differentiation, and Stem Cell Maintenance 2016 · 26 citations
    12. Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion PloS one · 2012 · 72 citations
    13. Orchestration of tissue‐scale mechanics and fate decisions by polarity signalling EMBO journal · 2021 · 5 citations
    14. Partial interchangeability of <i>Fz3</i> and <i>Fz6</i> in tissue polarity signaling for epithelial orientation and axon growth and guidance Development · 2014 · 28 citations
    15. Region-specific reversal of epidermal planar polarity in the <i>rosette</i> fancy mouse Development · 2023 · 2 citations
    16. ILK modulates epithelial polarity and matrix formation in hair follicles Molecular biology of the cell · 2013 · 22 citations
    17. Overactive Wnt5a signaling disrupts hair follicle polarity during mouse skin development Development · 2022 · 7 citations
    18. 851 The role of astrotactin2 in regulating mammalian skin polarity 2017
    19. α-parvin is required for epidermal morphogenesis, hair follicle development and basal keratinocyte polarity PloS one · 2020 · 7 citations
    20. AGD1, a class 1 ARF‐GAP, acts in common signaling pathways with phosphoinositide metabolism and the actin cytoskeleton in controlling Arabidopsis root hair polarity The Plant Journal · 2011 · 56 citations
    21. GWASs Identify Genetic Loci Associated with Human Scalp Hair Whorl Direction Journal of Investigative Dermatology · 2023 · 4 citations
    22. MOF-mediated Histone H4 Lysine 16 Acetylation Governs Mitochondrial and Ciliary Functions By Controlling Gene Promoters bioRxiv (Cold Spring Harbor Laboratory) · 2022
    23. Integrin β1 Establishes Liver Microstructure and Modulates Transforming Growth Factor β during Liver Development and Regeneration American Journal Of Pathology · 2020 · 10 citations
    24. Integrin signalling regulates YAP/TAZ to control skin homeostasis Development · 2016 · 266 citations
    25. Cell Polarization Defects in Early Heart Development Circulation Research · 2007 · 9 citations
    26. In focus in HCB Histochemistry and Cell Biology · 2021
    27. Co-opting Developmental Signaling Pathways to Promote Wound Healing Recent clinical techniques, results, and research in wounds · 2018 · 1 citations
    28. Epidermal–dermal coupled spheroids are important for tissue pattern regeneration in reconstituted skin explant cultures npj regenerative medicine · 2023
    29. Epidermal Polarity Genes in Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 32 citations
    30. Regulation of stem cell function by protein ubiquitylation EMBO Reports · 2014 · 55 citations