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    Did you mean BRAF inhibitors?
    Glossary BRAF inhibitors

    drugs that block mutated BRAF protein to treat cancer

    BRAF inhibitors are a class of drugs designed to block the activity of the BRAF protein, which is involved in sending signals inside cells and can contribute to cancer growth when mutated. These inhibitors are particularly used in treating certain types of melanoma and other cancers with specific BRAF mutations, helping to slow down or stop the progression of the disease.

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    Research 30 of 334

    1. 696 MEK and BRAF inhibitors augment the production and accumulation of sebum in hamster sebocytes Journal of Investigative Dermatology · 2016
    2. Diseases of the Canine Prostate Gland Veterinary medicine and science · 2022 · 1 citations
    3. 554 Repurposing a clinical antimalarial for the therapeutic induction of lethal ER stress targeting BRAF-kinase inhibitor-resistant malignant melanoma Journal of Investigative Dermatology · 2016
    4. The Cutaneous Side Effects of Selective BRAF Inhibitors and Anti-CTLA4 Agents: the Growing Role of the Dermatologist in the Management of Patients with Metastatic Melanoma Current Dermatology Reports · 2013 · 6 citations
    5. BRAF Inhibitor Dabrafenib in Patients with Metastatic <i>BRAF</i>-Mutant Thyroid Cancer Thyroid · 2014 · 188 citations
    6. Wound healing with topical BRAF inhibitor therapy in a diabetic model suggests tissue regenerative effects PLOS ONE · 2021 · 3 citations
    7. Dermatologic adverse events associated with chemotherapy and targeted anticancer therapy Dermatology Review · 2016 · 4 citations
    8. Cutaneous reactions to chemotherapeutic drugs and targeted therapy for cancer Journal of the American Academy of Dermatology · 2014 · 88 citations
    9. Inhibition of mitochondrial respiration prevents BRAF-mutant melanoma brain metastasis Acta neuropathologica communications · 2019 · 29 citations
    10. Diagnosis and Management of Melanoma of the Scalp: A Review of the Literature Clinical, Cosmetic and Investigational Dermatology · 2021 · 3 citations
    11. Is knowledge about the genetic and epigenetic alterations in melanoma a basis for targeted therapy? Experimental Dermatology · 2006
    12. Wnt/β-catenin signalling: function, biological mechanisms, and therapeutic opportunities Signal Transduction and Targeted Therapy · 2022 · 318 citations
    13. Melanoma: Genetic Abnormalities, Tumor Progression, Clonal Evolution and Tumor Initiating Cells Medical Sciences · 2017 · 37 citations
    14. Logic-based modeling and drug repurposing for the prediction of novel therapeutic targets and combination regimens against E2F1-driven melanoma progression BMC chemistry · 2023 · 1 citations
    15. Biological therapy in the treatment of melanoma Journal of Mind and Medical Sciences · 2018 · 3 citations
    16. Endocrine treatment of benign prostatichypertrophy: Current concepts Urology · 1991 · 11 citations
    17. Lentiginous melanoma. A clinically malignant entity that histopathologically seems benign. Case study harbouring BRAF V 600R mutation Journal of the European Academy of Dermatology and Venereology · 2015 · 1 citations
    18. LY191704: a selective, nonsteroidal inhibitor of human steroid 5 alpha-reductase type 1. Proceedings of the National Academy of Sciences of the United States of America · 1993 · 53 citations
    19. Redefining hormone resistance in prostate cancer Therapeutic Advances in Medical Oncology · 2009 · 38 citations
    20. The PDGF/PDGFR pathway as a drug target Molecular Aspects of Medicine · 2017 · 182 citations
    21. Male androgenetic alopecia (Part II) The Journal of Men's Health & Gender · 2005 · 9 citations
    22. A computationally inferred regulatory heart aging model including post-transcriptional regulations 2016 · 1 citations
    23. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    24. Dermoscopy — 4th Conference of the Section of Dermoscopy and Other Skin Imaging Techniques (DiTOS) of the Polish Dermatological Society — Abstracts Forum Dermatologicum · 2026
    25. Regulation of melanocyte stem cell behavior by the niche microenvironment Pigment Cell & Melanoma Research · 2018 · 24 citations
    26. Keratosis Pilaris-like Eruption during Treatment of Chronic Myeloid Leukemia with Tyrosine Kinase Inhibitors: Literature Review and Report of a Case Related to Imatinib Journal of clinical medicine · 2023
    27. B-Raf and C-Raf Are Required for Melanocyte Stem Cell Self-Maintenance Cell Reports · 2012 · 26 citations
    28. BAYONET trial: staged combination with encorafenib, binimetinib, plus cetuximab following encorafenib plus cetuximab for BRAF V600E-mutant metastatic colorectal cancer ESMO Gastrointestinal Oncology · 2024
    29. Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA–Target Gene Interactions in Mice Biology · 2025
    30. Aberrant Activation of the Hedgehog Pathway in Cutaneous Melanoma: Therapeutic Potential of Pharmacological Inhibitors International Journal of Molecular Sciences · 2026