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    Glossary BMP signaling

    regulates growth and development of bones and tissues

    BMP signaling, short for Bone Morphogenetic Protein signaling, is a biological pathway that involves proteins called BMPs. These proteins play a crucial role in regulating the growth, development, and repair of bones and other tissues. In the context of hair, BMP signaling is important for hair follicle development and cycling, influencing processes like hair growth and regeneration.

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    1. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012 · 321 citations
    2. mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration 2015 · 71 citations
    3. Telomere dysfunction impairs epidermal stem cell specification and differentiation by disrupting BMP/pSmad/P63 signaling PLOS genetics · 2019 · 19 citations
    4. TLR2 regulates hair follicle cycle and regeneration via BMP signaling eLife · 2023 · 1 citations
    5. 1360 Regulation of bmp signalling in melanogenesis, pigment transfer and melanocyte migration Journal of Investigative Dermatology · 2018
    6. Faculty Opinions recommendation of Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2013
    7. Characterization of Growth Secondary Hair in Min Pig Activated by Follicle Stem Cell Stimulated by Wnt and BMP Signaling Pathway Animals · 2023 · 1 citations
    8. BMP signaling in the control of skin development and hair follicle growth Differentiation · 2004 · 165 citations
    9. BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin PLoS Genetics · 2014 · 84 citations
    10. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    11. 447 Skin-Associated Cartilage Consists of Lipid-Filled Cells That Modify Hair Growth via BMP and WNT Signaling Journal of Investigative Dermatology · 2025
    12. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    13. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations
    14. Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation Proceedings of the National Academy of Sciences · 2013 · 176 citations
    15. Bone morphogenetic protein (BMP) signaling controls hair pigmentation by means of cross-talk with the melanocortin receptor-1 pathway Proceedings of the National Academy of Sciences · 2004 · 70 citations
    16. Photobiomodulation mitigates DHT-induced apoptosis in dermal papilla cells via mitochondrial rescue and Wnt/TGF-β/BMP signaling modulation Journal of Photochemistry and Photobiology B Biology · 2025 · 1 citations
    17. 570 DNA dioxygenases Tet1/2/3 control cell differentiation in the hair follicle keratinocytes via modulating the activity of BMP signaling pathway 2019
    18. TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling 2023
    19. Joint Public Review: TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling 2023
    20. TLR2 Regulates Hair Follicle Cycle and Regeneration via BMP Signaling. bioRxiv (Cold Spring Harbor Laboratory) · 2023
    21. 687 BMP signaling in the hair follicle stem cell niche regulates hair growth and skin pigmentation 2016
    22. Implications of constitutively active bone morphogenetic protein (BMP) signaling in skin morphogenesis and skin postnatal homeostasis University of Southern California Digital Library · 2011
    23. 592 Cross-interactions of BMP and WNT signaling pathways attenuate androgen effect on HFSC differentiation Journal of Investigative Dermatology · 2019
    24. Role of the bone morphogenetic protein signalling in skin carcinogenesis. Effect of transgenic overexpression of BMP antognist Noggin on skin tumour development; molecular mechanisms underlying tumour suppressive role of the BMP signalling in skin. Bradford Scholars (University of Bradford) · 2009
    25. Embryonic hair follicle fate change by augmented β-catenin through Shh and Bmp signaling Development · 2009 · 54 citations
    26. Nail Proximal Fold Stem Cells (NPFSCs) Participate In Nail Growth, Orchestrating Enhanced Digit Regeneration via BMP Signaling Activation Stem Cells · 2026
    27. Nitrate Promoting Hair Growth Through Enhancing Wnt/β-catenin and Downregulating TGF-β/Samd/BMP signaling pathway in C57BL/6 Mice bioRxiv (Cold Spring Harbor Laboratory) · 2024
    28. Ear pinna growth and differentiation is conserved in murids and requires BMP signaling for chondrocyte proliferation Development · 2025 · 2 citations
    29. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023 · 1 citations
    30. Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression Cell stem cell · 2018 · 85 citations