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    Glossary Basal Layer

    deepest epidermal layer where new skin cells form

    The Basal Layer, also known as the Stratum Basale, is the deepest layer of the epidermis, which is the outermost layer of the skin. This layer is crucial because it contains basal cells that continuously divide and push older cells towards the skin's surface, where they eventually shed. It also houses melanocytes, which produce the pigment melanin, giving skin its color and providing some protection against UV radiation.

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    Research 30 of 1000+

    1. Long-term follow-up of leucoderma patients treated with transplants of autologous cultured melanocytes, ultrathin epidermal sheets and basal cell layer suspension 2002 · 177 citations
    2. Three-Dimensional Analysis of Cell Division Orientation in Epidermal Basal Layer Using Intravital Two-Photon Microscopy PLoS ONE · 2016 · 31 citations
    3. Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle Experimental Cell Research · 1998 · 46 citations
    4. 41551 Feasibility of using an integrated RCM-OCT device to identify thin Basal Cell Carcinomas amenable to ablative therapy with a Er:YAG laser: A Prospective Observational Study Journal of the American Academy of Dermatology · 2023
    5. Heterotypic cell contacts and basal lamina morphology during hair follicle development in the mouse: a light, scanning, and electron microscopic study at the site of tissue interaction Canadian journal of zoology · 1983 · 13 citations
    6. Non-surgical treatments for basal cell skin cancer Vestnik dermatologii i venerologii · 2021 · 4 citations
    7. Expression patterns of programmed cell death 4 protein in normal human skin and some representative skin lesions Experimental Dermatology · 2007 · 37 citations
    8. Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis Journal of Investigative Dermatology · 1999 · 13 citations
    9. A Niche Above: A Novel Modality of Stem Cell Regulation in Mammalian Skin Epidermis Cell stem cell · 2021
    10. Cell cycle controls long-range calcium signaling in the regenerating epidermis The Journal of Cell Biology · 2023 · 22 citations
    11. 566 DermaCult™ Keratinocyte Expansion Medium, a Serum- and BPE-free Medium Supporting Long-term Feeder-free Expansion of Primary Human Epidermal and Pluripotent Stem Cell-Derived Keratinocytes Journal of Investigative Dermatology · 2022
    12. Investigating the role of notch ligands regulating epidermal stem cell differentiation eScholarship@McGill (McGill) · 2025
    13. Basal cells in the epidermis and epidermal differentiation Research Square (Research Square) · 2021
    14. Targeting nonmelanoma skin cancer using selective photothermolysis with 595 nm pulsed dye laser: Outcomes of 1080 cases Journal of The American Academy of Dermatology · 2017
    15. Identification of the cell lineage at the origin of basal cell carcinoma Nature Cell Biology · 2010 · 351 citations
    16. Mecanismos e aplicações clínicas das tecnologias de laser e luz na dermatologia moderna Cuadernos de Educación y Desarrollo · 2025
    17. Cellular and Immunological Aspects of Basel Cell Carcinoma Data Archiving and Networked Services (DANS) · 1998
    18. Vitiligo International Journal of Dermatology · 1988 · 63 citations
    19. Use of Condensed Nanofat Combined With Fat Grafts to Treat Atrophic Scars JAMA facial plastic surgery · 2017 · 62 citations
    20. Human Hair Follicle Stem/Progenitor Cells Express Hypoxia Markers Journal of Investigative Dermatology · 2013 · 33 citations
    21. Development, Structure, and Keratin Expression in <i>C57BL/6J</i> Mouse Eccrine Glands Veterinary pathology · 2011 · 29 citations
    22. Lichen planopilaris [cicatricial (scarring) alopecia] in a child International Journal of Dermatology · 2001 · 18 citations
    23. A Mouse Model for Conditional Expression of Activated β-Catenin in Epidermal Keratinocytes Transgenic Research · 2024 · 1 citations
    24. Complications and Limitations of Melanocyte Transplantation 2018
    25. Eyebrow reconstruction with free skin and hair-bearing composite graft Journal of The American Academy of Dermatology · 1999 · 10 citations
    26. BRITISH ASSOCIATION OF DERMATOLOGY. British Journal of Dermatology · 1966
    27. Abstracts Lasers in Surgery and Medicine · 2023 · 7 citations
    28. Integrin signalling regulates YAP/TAZ to control skin homeostasis Development · 2016 · 266 citations
    29. Histologic Changes in the Skin of Hairless Mice Following Peeling With Salicylic Acid Archives of Dermatology · 2000 · 74 citations
    30. Application of multiphoton microscopy in dermatological studies: A mini-review Journal of Innovative Optical Health Sciences · 2013 · 58 citations