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    Glossary Androgen Metabolism

    process of producing, converting, and breaking down male hormones

    Androgen metabolism refers to the process by which the body produces, converts, and breaks down androgens, which are male sex hormones like testosterone. This process involves various enzymes that regulate the levels and activity of these hormones, impacting functions such as hair growth, muscle development, and reproductive health.

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    1. Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives 2002 · 233 citations
    2. Steroid 5α-reductases and 3α-hydroxysteroid dehydrogenases: key enzymes in androgen metabolism 2001 · 115 citations
    3. Androgen metabolism in hirsute patients treated with cyproterone acetate 1984 · 64 citations
    4. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride The Journal of Steroid Biochemistry and Molecular Biology · 2012 · 45 citations
    5. Influence of estrogens on the androgen metabolism in different subunits of human hair follicles. PubMed · 2001 · 41 citations
    6. THE EFFECT OF SPIRONOLACTONE ON HIRSUTISM AND FEMALE ANDROGEN METABOLISM Clinical endocrinology · 1985 · 32 citations
    7. Studies of androgen metabolism and action in cultured hair and skin cells Journal of Steroid Biochemistry · 1986 · 29 citations
    8. Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre- and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats Progress in Neuro-psychopharmacology & Biological Psychiatry · 1993 · 26 citations
    9. Benign Prostatic Hyperplasia: A Disorder of Androgen Metabolism in the Male Journal of the American Geriatrics Society · 1984 · 23 citations
    10. Is the metabolism of testosterone to 5α-dihydrotestosterone required for androgen action in the skin? British Journal of Dermatology · 1982 · 14 citations
    11. Novel aldo-keto reductase 1C3 inhibitor affects androgen metabolism but not ovarian function in healthy women: a phase 1 study European Journal of Endocrinology · 2023 · 8 citations
    12. Phenytoin‐mediated androgen metabolism in gingival fibroblasts Journal Of Clinical Periodontology · 2002 · 8 citations
    13. The feasibility of quantitative analysis of androgen metabolism by use of single dermal papillae from human hair follicles Experimental Dermatology · 2001 · 4 citations
    14. ANDROGEN METABOLISM AS IT AFFECTS HAIR GROWTH IN ANDROGENETIC ALOPECIA Dermatologic Clinics · 1999 · 4 citations
    15. 24-Hydroxycholesterol suppresses steroid 5α-reductase-catalyzed conversion in human glioblastoma cell lines: A novel link between brain cholesterol homeostasis and androgen metabolism Neurochemistry International · 2026
    16. Androgen synthesis, metabolism and action in the developing ovarian follicle University of Birmingham Institutional Research Archive (University of Birmingham) · 2016
    17. Disruption of androgen metabolism, regulation and effects : involvement of steroidogenic enzymes edoc (University of Basel) · 2014
    18. Genetic analysis of the role of androgen metabolism in the pathogenesis of prostate cancer SUNScholar (Stellenbosch University) · 2004
    19. Androgen Metabolism in Androgenetic Alopecia 프로그램북(구 초록집) · 2006
    20. Expression of type 1 5α-reductase and metabolism of testosterone in reconstructed human epidermis (SkinEthic®): a new model for screening skin-targeted androgen modulators International Journal of Cosmetic Science · 2000 · 3 citations
    21. Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products Endocrinology · 2017 · 2 citations
    22. The effects of androgens on drug metabolism and transport: clinical pharmacologic considerations for people assigned female at birth Expert Opinion on Drug Metabolism & Toxicology · 2026
    23. Differences in male and female pattern hair loss based on androgens, estrogen, iron, vitamin D, lipid metabolism, and genetic regulation Journal of Cutaneous and Aesthetic Surgery · 2026
    24. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    25. No metabolic impact of surgical normalization of hyperandrogenism in postmenopausal women with ovarian androgen-secreting tumours Clinical Endocrinology · 2012 · 17 citations
    26. METABOLISM AND ACTION OF ANDROGEN IN THE SKIN International Journal of Dermatology · 1979 · 25 citations
    27. Role of Androgen Receptor in Hypothalamic Regulation of Metabolism and Reproduction Deep Blue (University of Michigan) · 2021
    28. Myocyte Androgen Receptor Modulates Body Composition and Metabolic Parameters TSpace · 2010
    29. Metabolism of androgens by isolated human hair follicles Journal of Steroid Biochemistry · 1972 · 22 citations
    30. Animal Models and the Developmental Origins of Polycystic Ovary Syndrome: Increasing Evidence for the Role of Androgens in Programming Reproductive and Metabolic Dysfunction Endocrinology · 2012 · 44 citations