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    Did you mean Alpha-smooth muscle actin?
    Glossary Alpha-smooth muscle actin

    protein involved in smooth muscle contraction and wound healing

    Alpha-smooth muscle actin (α-SMA) is a protein that plays a crucial role in the contraction of smooth muscle cells, which are found in various tissues like blood vessels and the digestive tract. It is also a marker used by scientists to identify myofibroblasts, cells involved in wound healing and tissue repair. Elevated levels of α-SMA can indicate tissue remodeling or fibrosis, which is the thickening and scarring of connective tissue.

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    1. Formation of actin mesh structures and alpha-smooth muscle actin dynamics in fibroblasts contribute to dermal regeneration in mouse fetus PLoS ONE · 2025 · 1 citations
    2. Alpha Smooth Muscle Actin role in Androgenetic Alopecia Pathogenesis: Benha Journal of Applied Sciences · 2024
    3. Human hair follicle stem cell differentiation into contractile smooth muscle cells is induced by transforming growth factor-β1 and platelet-derived growth factor BB Molecular Medicine Reports · 2013 · 19 citations
    4. The action of diazoxide and minoxidil sulphate on rat blood vessels: a comparison with cromakalim British Journal of Pharmacology · 1990 · 86 citations
    5. Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action Dermatology · 2009 · 37 citations
    6. Mechanism of action of minoxidil sulfate-induced vasodilation: a role for increased K+ permeability. PubMed · 1988 · 48 citations
    7. Generation and Characterization of Multipotent Stem Cells from Established Dermal Cultures PLoS ONE · 2012 · 58 citations
    8. The repairing of full-thickness skin deficiency and its biological mechanism using decellularized human amniotic membrane as the wound dressing Materials Science and Engineering: C · 2017 · 47 citations
    9. Controllable Production of Transplantable Adult Human High-Passage Dermal Papilla Spheroids Using 3D Matrigel Culture Tissue engineering. Part A · 2014 · 46 citations
    10. Combination of lyophilized adipose-derived stem cell concentrated conditioned medium and polysaccharide hydrogel in the inhibition of hypertrophic scarring Stem Cell Research & Therapy · 2021 · 45 citations
    11. A novel immune competent murine hypertrophic scar contracture model: A tool to elucidate disease mechanism and develop new therapies Wound Repair and Regeneration · 2014 · 35 citations
    12. Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles Particle and Fibre Toxicology · 2024 · 26 citations
    13. Isolation and Characterization of Sweat Gland Myoepithelial Cells from Human Skin Cell Structure and Function · 2014 · 26 citations
    14. Immunophenotypical analyses of myofibroblasts in rat excisional wound healing: possible transdifferentiation of blood vessel pericytes and perifollicular dermal sheath cells into myofibroblasts. PubMed · 2012 · 26 citations
    15. Hyaluronic acid (HA)-based hydrogels for full-thickness wound repairing and skin regeneration Journal of Materials Science: Materials in Medicine · 2018 · 24 citations
    16. Micropatterned composite membrane guides oriented cell growth and vascularization for accelerating wound healing Regenerative Biomaterials · 2022 · 19 citations
    17. Intracavernous injection of platelet‐rich plasma reverses erectile dysfunction of chronic cavernous nerve degeneration through reduction of prostate hyperplasia evidence from an aging‐induced erectile dysfunction rat model The FASEB Journal · 2023 · 12 citations
    18. Effects of ginsenoside Rb1 on hypertrophic scar remodeling in rabbit model European journal of pharmacology · 2015 · 10 citations
    19. Wound healing mechanism in Mongolian gerbil skin Histochemistry and Cell Biology · 2018 · 6 citations
    20. Histological and immunohistochemical studies of excisional wounds in the rat with special reference to the involvement of the hair follicles in the wound healing process Durham e-Theses (Durham University) · 2000 · 4 citations
    21. [Influence and mechanism of extracellular vesicles derived from human dermal papilla cells on skin fibrosis in mice]. PubMed · 2025
    22. 4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression Research Square (Research Square) · 2022
    23. 4-aminopyridine promotes accelerated skin wound healing via neurogenic-mediator expression bioRxiv (Cold Spring Harbor Laboratory) · 2021
    24. A Mouse Model for Studying Stem Cell Effects on Regeneration of Hair Follicle Outer Root Sheaths Central European Journal of Biology · 2020
    25. Decellularized Wharton's jelly matrix as a three dimensional scaffold for wound healing and hair regeneration applications KU ScholarWorks (The University of Kansas) · 2016
    26. Human hair follicle dermal papilla cell, dermal sheath cell and interstitial dermal fibroblast characteristics. PubMed · 1996 · 36 citations
    27. Effects of Adipose-Derived Stem Cells and Platelet-Rich Plasma Exosomes on The Inductivity of Hair Dermal Papilla Cells. PubMed · 2021 · 5 citations
    28. Influence of the alkylsulfonylamino substituent located at the 6-position of 2,2-dimethylchromans structurally related to cromakalim: From potassium channel openers to calcium entry blockers? European journal of medicinal chemistry · 2014 · 6 citations
    29. Signaling by the Platelet-Derived Growth Factor Receptor Family 2009
    30. Direct-Acting Vasodilators ˜The œjournal of clinical hypertension · 2011 · 40 citations