46 citations,
September 2014 in “Tissue engineering. Part A” Researchers created hair-inducing human cell clusters using a 3D culture method.
47 citations,
March 2017 in “Materials Science and Engineering: C” Human amniotic membrane helps heal skin wounds faster and with less scarring.
6 citations,
November 2018 in “Histochemistry and Cell Biology” Mongolian gerbils heal wounds differently than mice, with unique protein levels and gene expression that affect skin repair.
31 citations,
January 2014 in “International Journal of Trichology” The arrector pili muscle might play a role in hair loss and needs more research to understand its impact.
66 citations,
May 2012 in “Scientific Reports” Scientists successfully created and transplanted bioengineered hair follicles that function like natural ones, suggesting a new treatment for hair loss.
59 citations,
November 2010 in “Circulation Research” Wnt signaling may be linked to heart diseases in aging and could be a target for future treatments.
22 citations,
February 2013 in “Wound Repair and Regeneration” Mice genetically modified to produce more CD109 in their skin had less inflammation and better healing with less scarring.
47 citations,
November 2012 in “Wound repair and regeneration” Nude mice with grafted human skin developed scars similar to human hypertrophic scars.
13 citations,
March 2012 in “The Journal of Dermatology” Hair transplant surgery can rebuild muscle and nerve connections, allowing transplanted hairs to stand up like normal hairs.
38 citations,
January 2006 in “Journal of Cellular Biochemistry” Researchers isolated a new type of stem cell from mouse skin that can renew itself and turn into multiple cell types.
2 citations,
March 2019 in “American journal of physiology. Renal physiology./American journal of physiology. Renal physiology” New treatments targeting fibrosis could improve urinary symptoms in BPH.
44 citations,
October 2017 in “British Journal of Dermatology” Botulinum toxin has potential for treating various skin conditions and improving wound healing.
35 citations,
January 2014 in “Journal of Tissue Engineering” Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.
29 citations,
April 2020 in “Biomolecules” The 3D scaffold helped maintain hair cell traits and could improve hair loss treatments.
16 citations,
December 2018 in “ACS Biomaterials Science & Engineering” The new patch made of cell matrix and a polymer improves wound healing and supports blood vessel growth.
2 citations,
September 2020 in “Biomedical materials” Recombinant keratin materials may better promote skin cell differentiation than natural keratin.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
35 citations,
October 2017 in “Signal Transduction and Targeted Therapy” Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
17 citations,
December 2010 in “Journal of Investigative Dermatology” Flightless I protein affects hair growth, with low levels delaying it and high levels increasing hair length in rodents.
13 citations,
January 2022 in “Stem cell reviews and reports” Mouse stem cells from hair follicles can improve wound healing and reduce scarring.
6 citations,
July 2015 in “Journal of Investigative Dermatology” Chicken feather gene mutation helps understand human hair disorders.
66 citations,
June 2015 in “Aesthetic Plastic Surgery” Platelet preparations generally show positive effects on wound healing and facial rejuvenation, but more thorough research is needed to confirm their effectiveness.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
1 citations,
January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
January 2023 in “Journal of orthopedics & bone disorders” Platelet-rich plasma may not be very effective for bone healing and hair growth due to a substance it contains that blocks these processes.
8 citations,
March 2020 in “Frontiers in Cell and Developmental Biology” Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.
142 citations,
March 2019 in “Frontiers in Cellular Neuroscience” The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.
26 citations,
September 2018 in “Colloids and Surfaces B: Biointerfaces” A new liposome treatment helps heal deep burns on mice by improving hair regrowth and reducing scarring.
16 citations,
January 2020 in “Diabetes” A new therapy sped up wound healing and reduced scarring in diabetic rats.
13 citations,
December 2012 in “Cells” Targeting the actin cytoskeleton could improve skin healing and reduce scarring.