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The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Finasteride improves heart function in obese and aging male rats by reducing oxidative stress and p53 protein levels.

A new drug, dutasteride, is at least as effective as the older drug, finasteride, for treating enlarged prostate and may have additional uses.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Blocking DHT production more strongly may help control advanced prostate cancer and improve quality of life.

Long-term use of certain prostate drugs can worsen erectile dysfunction by changing penile tissue, especially in rats with high blood pressure.

Gender-affirming therapy can cause skin issues like acne and hair loss in transgender adolescents, and more research is needed on its dermatological effects.

Both dutasteride and finasteride improve urinary symptoms, but dutasteride may be better at reducing the risk of prostate surgery and sudden inability to urinate.

The bark of Myrica rubra contains compounds that can block testosterone effects and might help prevent hair loss.

Finasteride doesn't affect hormone levels in normal men.

5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Finasteride and minoxidil together promote hair growth better than either alone.

Taking finasteride for benign prostate hyperplasia may increase the risk of osteoporosis, especially at higher doses.

Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.

Dutasteride works better than finasteride for hair loss, with both being safe to use.

Dutasteride is safe and effective for treating hair loss, but may decrease libido.

Finasteride doesn't affect erections much, but may decrease libido in men.

Certain drugs change freshwater snail shells to a "banana" shape.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Taking 5-Alpha Reductase Inhibitors before bladder removal surgery might make high-grade bladder tumors less aggressive.

5-alpha reductase inhibitors may reduce bladder cancer recurrence and improve survival.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Using 5-alpha-reductase inhibitors may improve bladder cancer survival in men.

Oral finasteride and dutasteride may negatively affect erectile function in rats.