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Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

research Fine Structure and Immunocytochemistry of Monotreme Hairs, with Emphasis on the Inner Root Sheath and Trichohyalin-Based Cornification During Hair Evolution

15 citations, July 2004 in “Journal of morphology”

Monotreme hair structure and protein distribution are similar to other mammals, but their inner root sheath cornifies differently, suggesting a unique evolution from reptile skin.

research Evolution of Hard Proteins in the Sauropsid Integument in Relation to the Cornification of Skin Derivatives in Amniotes

86 citations, April 2009 in “Journal of anatomy”

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

research Skin Appendage Proteins of Tetrapods: Building Blocks of Claws, Feathers, Hair, and Other Cornified Epithelial Structures

February 2025 in “Animals”

Understanding proteins in skin structures like claws and hair is crucial for future research.

research Structure and Mechanical Properties of Human Trichocyte Keratin Intermediate Filament Protein

51 citations, September 2012 in “Biomacromolecules”

Disulfide bonds make keratin in hair stronger and tougher.

research The Circadian Clock in Skin

127 citations, January 2015 in “Journal of Biological Rhythms”

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

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community Verteporfin and Microneedling

in Treatments 9 months ago

Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

community Increased Coffee intake resulted in massive shed

in Finasteride/Dutasteride 17 upvotes 5 months ago

Increased coffee intake might be linked to hair shedding, but the cause is unclear. The user is on finasteride and has increased water intake, possibly affecting electrolyte balance.