7 citations
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October 2018 in “BMC genomics” This study reveals that β-catenin and retinoic acid are key regulators in the gene networks controlling the fate of skin appendages, such as scales and feathers.
March 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” This study reports that transplantation and in vivo reprogramming using specific reprogrammed cell types can generate skin appendage-like structures in adult mice, suggesting potential therapeutic avenues for skin regeneration and disorders.
116 citations
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August 2010 in “Nature” Scientists turned rat thymus cells into stem cells that can help repair skin and hair.
23 citations
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May 2019 in “Stem cell research & therapy” This study found that combining a human acellular amniotic membrane with iPSC-derived epithelial stem cells effectively repaired skin defects and promoted hair follicle formation in nude mice.
2 citations
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November 2018 in “Cell Stem Cell” This study reported that wound-resident mesenchymal cells can be reprogrammed to generate epithelial tissues, aiding in the closure of large, non-healing ulcers without signs of malignant transformation.