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research Differential Gene Expression Screening Between Black and Gray Hairs Using Subtractive Library and DNA Chip

January 2004 in “Linchuang pifuke zazhi”

This study identified specific genes that are more abundantly expressed in black hair than in gray hair, with black hair displaying higher expression of pigment-related proteins and gray hair showing increased expression of keratin-related genes.

research Identification of androgen-regulated genes in SV40-transformed human hair dermal papilla cells

12 citations , May 2003 in “Journal of dermatological science”

This study found that the heat shock cognate protein Hsc70 was differentially expressed by dihydrotestosterone treatment in SV40-transformed dermal papilla cells, suggesting its involvement in androgen action on these cells.

research A Comparative Analysis of Large Language Model Accuracy for Image-Based Hair Disease Identification in Diverse Skin Tones

August 2024 in “Journal of the National Medical Association”

ChatGPT is more accurate at diagnosing hair disorders in lighter skin tones than darker ones.

research Racial and Ethnic Disparities in Androgenetic Alopecia Clinical Trials in the United States

December 2022 in “Journal of dermatology and skin science”

This study found that non-Caucasian patients are underrepresented in US RCTs for androgenetic alopecia, limiting the generalizability of the findings to the diverse general population.

research A Novel Serine Protease Overexpressed in the Hair Follicles of Nude Mice

32 citations , May 1999 in “Biochemical and Biophysical Research Communications”

This study found that the gene BSSP, a serine protease, is predominantly expressed in sebaceous glands and is overexpressed in nude mouse skin.

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community EU Shouldn't Ban Fin & Dut: PFS is NOT REAL.

10 upvotes 1 year ago

Finasteride and Dutasteride do not cause depression or "Post Finasteride Syndrome," with concerns often linked to the nocebo effect and preexisting mental health issues. The EU is unlikely to ban these drugs, but access may become more restricted due to ongoing debates.

community Male (24) Using Dutasteride Since 2020 – Concerns About Having Kids

in Finasteride/Dutasteride 90 upvotes 1 year ago

A 24-year-old male using dutasteride for hair loss is worried about its effects on fertility and future children's health. Users advise consulting a doctor, possibly switching to finasteride, or stopping dutasteride before conception due to its impact on sperm count.

community Be careful when switching from Finasteride to Dutasteride because for more efficacy.

in Finasteride/Dutasteride 13 upvotes 1 year ago

Switching from finasteride to dutasteride may be more effective for hair regrowth due to dutasteride's stronger enzyme inhibition, but combining both drugs could enhance results. Some users report better outcomes with dutasteride, while others recommend a gradual transition to prevent potential hair loss.

community 57% increased chance of pattern hair loss independently associated with the consumption of sugary beverages in men (p<0.001).

297 upvotes 2 years ago

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

community Testosterone and hair loss seeming irrelevance

82 upvotes 3 years ago

The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

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