Racial and Ethnic Disparities in Androgenetic Alopecia Clinical Trials in the United States

This study analyzed racial and ethnic representation in 20 phase II and III randomized controlled trials (RCTs) for androgenetic alopecia (AGA) in the United States over the past 10 years, involving 1855 participants. The analysis revealed that non-Caucasian patients are underrepresented, with 81.1% of participants being white, 11.9% African American, and 3.1% Asian. Only 0.56% were American Indian/Alaska Native, 0.47% Hawaiian/Pacific Islander, and 1.5% were of another or unknown race. Ethnicity data was reported in 25% of trials, with 18.9% identifying as Hispanic. The study concludes that the lack of diversity limits the generalizability of trial outcomes, emphasizing the need for more inclusive RCTs to provide individualized care for AGA patients across different racial and ethnic groups.