research Replicative stress, stem cells and aging
This review discusses genome maintenance mechanisms critical for preventing age-related diseases by preserving stem and progenitor cell potential, but reports no new empirical findings.
Search
forResearch
5 / 1000+ results 
research Hair follicle stem cell replication stress drives IFI16/STING-dependent inflammation in hidradenitis suppurativa
This study found that hair follicle stem cells from hidradenitis suppurativa patients showed alterations in cell cycle regulation and DNA replication, potentially linking genetic predisposition to the skin inflammation characteristic of the disease.
research Temporary Relocation during Rest Periods: Relocation Stress and Other Factors Influence Hair Cortisol Concentrations in Horses
This study reported that relocation in police horses was associated with elevated hair cortisol concentrations, possibly suggesting altered welfare due to changed surroundings, and that seasonal variations affected both cortisol levels and hair growth.
research Defects in mitochondrial DNA replication and oxidative damage in muscle of mtDNA mutator mice
This study found that oxidative damage is present in the mitochondria of PolG mice, which exhibit premature aging-like phenotypes due to mitochondrial dysfunction.
research γ-Aminobutyric acid promotes the inhibition of hair growth induced by chronic restraint stress
This study demonstrated that elevated GABA levels can worsen stress-induced hair growth inhibition in mice, while GABAA antagonists like ginkgolide A may help alleviate these effects.
Community Join
5 / 67 resultscommunity 20M and male pattern baldness is ruining my life
A 20-year-old is dealing with male pattern baldness and considering finasteride despite concerns about side effects. Users recommend treatments like minoxidil, dutasteride, and lifestyle changes, stressing early intervention.
community 12 month fin update. Long curly hair
A user experienced significant hair regrowth after using 1mg of finasteride daily for a year, avoiding minoxidil due to its toxicity to cats. They attributed success to quitting smoking, a better diet, and reduced stress, with only watery semen as a side effect.
community Do you believe these studies are real or just fear mongering
Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.
community David Sinclair, professor of genetics at Harvard Medical School, says he's working on baldness reversal
David Sinclair is criticized for being more business-oriented than scientific, with accusations of fraud and unethical practices. There is skepticism about his claims on baldness reversal, despite some acknowledging his achievements in gene therapy.
community Nov 2023 to today. 1mg finasteride daily since Feb 2024. Considering moving to Dutasteride based on the anecdotes I see on this sub and would like input.
A 30-year-old is using 1mg finasteride daily and 5% minoxidil inconsistently for hair regrowth, noticing recent progress and considering switching to dutasteride. Users advise continuing the current regimen for at least two years before considering dutasteride, as finasteride and minoxidil are showing positive results.
Learn
— no results
Experts
— no results
Clinics
— no results