November 2023 in “International Journal of Cosmetic Science”
This study found that a wheat polar lipid complex supplement significantly reduced hairloss and improved hair growth and volume in women experiencing acute hair shedding, including postmenopausal women.
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August 2023 in “Biomedicine & Pharmacotherapy”
This study found that in noise-exposed FVB/NJ mice and cell models, ivacaftor reduced oxidative stress and hearing damage by maintaining CFTR function and increasing Nrf2 expression, suggesting its potential for treating noise-induced hearing loss.
November 2025 in “Journal of Cosmetic Dermatology”
This study found that a proprietary saw palmetto (Serenoa repens) extract significantly increased hair growth and reduced hair shedding in men and women with self-perceived thinning hair over a 90-day period, compared to placebo, without reported adverse events.
Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hairloss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.
Mesotherapy Dutasteride is considered highly effective for reducing scalp DHT and potentially reversing hairloss. However, one user reported systemic side effects and no improvement in hairloss.
Using topical GHK-Cu 4% has reduced hair shedding, increased hair shaft diameter, and improved scalp health, but no new hair growth was observed. The user continues to use 10% Minoxidil and 1mg oral Finasteride alongside GHK-Cu.
Topical roflumilast is effective for reducing inflammation in various scalp conditions like seborrheic dermatitis, psoriasis, and eczema, but not proven to stop scarring alopecia. Alternatives like apremilast and Vtama are also discussed for their anti-inflammatory benefits.
Ashwagandha may help with hairloss by regulating thyroid function and reducing stress, but its effectiveness compared to finasteride or minoxidil is debated. Some users report positive effects on hair health, while others are skeptical of its benefits.
Does castor oil make hair grow or is it just a myth?There is no published human trial showing castor oil grows hair. It can make hair look and feel better by reducing breakage and adding shine, which is easily mistaken for growth, and it is not approved anywhere as a hair loss treatment.