11 citations
,
November 2015 in “Skin Research and Technology”
This study found that individuals with patterned hairloss, both male and female, showed a slower linear hair growth rate compared to controls with hair of equal thickness.
22 citations
,
October 2004 in “Journal of Investigative Dermatology”
This study identified the rough coat mutation in mice, but found that LOXL is not the causal gene, although its downregulation might contribute to related phenotypic changes.
Scalp massage significantly reducedhairloss for the user, who had been using finasteride without improvement. The user attributes the reduction in hairloss to the massage rather than the medication.
Increasing IGF-1 may help hair growth, but it could also increase hairloss in people with high testosterone. Treatments discussed include l-arginine, glutamine, vanadium, Deer Antler Velvet, ATP, Cocarboxylase, l-carnitine, and Mk677.
Lowering DHT can improve skin quality and reduce scalp issues. Finasteride is effective for hair regrowth and improving skin texture, while dutasteride may increase oiliness and shedding for some users.
An SSRI (paroxetine) reducedhairloss and itching for a user with male-pattern baldness, but liver issues forced discontinuation, leading to increased hairloss and anxiety. The user plans to try other anti-anxiety medications, noting stress and anxiety significantly impact hairloss.
How does cetirizine reduce inflammation linked to hairloss?Cetirizine is proposed to lower prostaglandin D2 and raise prostaglandin E2 around hair follicles; three small trials of a compounded 1% topical report modest increases in hair density and shaft thickness, with minoxidil doing better head-to-head. Topical cetirizine is off-label and unapproved for hair loss, and the evidence is too thin to call it effective or safe.